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Blood Disorders

Blood diseases affect the production of blood and its components, such as blood cells, hemoglobin, blood proteins, the mechanism of coagulation, etc.

Classification of Blood Diseases


(congenital abnormality of the hemoglobin molecule or of the rate of hemoglobin synthesis)

  • Sickle-cell disease
  • Thalassemia
  • Methemoglobinemia


(lack of red blood cells or hemoglobin)

  • Iron deficiency anemia
  • Megaloblastic anemia (e.g., Vitamin B12 deficiency, Folate deficiency)
  • Hemolytic anemias (destruction of red blood cells)
  • Aplastic anemia

Decreased numbers of cells

  • Myelodysplastic syndrome
  • Myelofibrosis
  • Neutropenia (decrease in the number of neutrophils)
  • Agranulocytosis
  • Glanzmann's thrombasthenia
  • Thrombocytopenia (decrease in the number of platelets)

Myeloproliferative Disorders

(increased numbers of cells)

  • Polycythemia vera (increase in the number of cells in general)
  • Leukocytosis (increase in the number of white blood cells)
  • Thrombocytosis (increase in the number of platelets)
  • Myeloproliferative disorder

Hematological Malignancies

  • Lymphomas (e.g., Hodgkin's disease, Non-Hodgkin's lymphoma, Burkitt's lymphoma, Anaplastic large cell lymphoma)
  • Myelomas (e.g., Multiple myeloma, Waldenström macroglobulinemia)
  • Plasmacytoma
  • Leukemias


(disorders of bleeding and coagulation)

  • Thrombocytosis
  • Recurrent thrombosis
  • Disseminated intravascular coagulation
  • Disorders of clotting proteins (e.g. hemophilia, Von Willebrand disease, disseminated intravascular coagulation)
  • Disorders of platelets (e.g., Thrombocytopenia, Wiskott-Aldrich syndrome)


  • Haemochromatosis
  • Asplenia
  • Hypersplenism (e.g., Gauchers disease)

Haemotological changes secondary to non-haemotological disorders

  • Anemia of chronic disease
  • Infectious mononucleosis
  • AIDS
  • Malaria
  • Leishmaniasis

Source: Wikipedia » Blood Diseases

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