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You are here: Home » Products Listed by Brand » McKesson Products » Drug Reference (A's) » Alendronate



The appearance of any medication may be subject to change. The appearance of any medication may vary from country to country.
TO CONFIRM THE IDENTITY OF ANY MEDICATION YOU MUST CONSULT YOUR DOCTOR OR PHARMACIST.

DESCRIPTION

Alendronate sodium is an aminobisphosphonate that acts as a specific inhibitor of osteoclast-mediated bone resorption. Bisphosphonates are synthetic analogs of pyrophosphate that bind to the hydroxyapatite found in bone.

Alendronate sodium is chemically described as (4-amino-1- hydroxybutylidene) bisphosphonic acid monosodium salt trihydrate.

The empirical formula of alendronate sodium is C4H12NNaO7P23H2O and its formula weight is 325.12.

Alendronate sodium is a white, crystalline, nonhygroscopic powder. It is soluble in water, very slightly soluble in alcohol, and practically insoluble in chloroform.

Fosamax Tablets for oral administration contain either 6.53, 13.05 mg or 52.21 mg of alendronate monosodium salt trihydrate, which is the molar equivalent of 5.0, 10.0 mg and 40.0 mg, respectively, of free acid, and the following inactive ingredients: microcrystalline cellulose, anhydrous lactose, croscarmellose sodium, and magnesium stearate.

CATEGORIES, BRAND NAMES

CATEGORIES: Osteoporosis; Paget's disease; FDA Class 1P ("Priority Review"); FDA Approved 1995 Sep; Top 200 Drugs; Pregnancy Category C

FDA Drug Classes: Calcium Metabolism

BRAND NAMES:

BRAND NAMES: Alend; Bifosa; Eucalen; Fosalan; Fosamax; Indrol; Mavil; NeoBon; Osteovan
(Foreign Brand names outside U.S. in italics)

FOREIGN BRAND AVAILABILITY:
Fosalan (Israel)





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