ATROPINE SULFATE Injection, USP
0.1 mg/mI (Adult)
0.05 mg/mL (Pediatric)
ABBOJECT® Unit of Use Syringe
Atropine Sulfate Injection, USP is a sterile,
nonpyrogenic isotonic solution of atropine sulfate
monohydrate in water for injection
with sodium chloride sufficient to render the solution
isotonic. It is administered parenterally by subcutaneous,
intramuscular or intravenous
Each milliliter (mL) contains
atropine sulfate, monohydrate 0.1 mg
(adult strength) or 0.05 mg (pediatric
strength), and sodium chloride,
9 mg. May contain sodium hydroxide
and/or sulfuric acid for pH
adjustment 0.308 mOsmol/mL
(calc.). pH 4.2 (3.0 to 6.5).
The solution contains no
agent or added buffer (except
for pH adjustment) and is intended
for use only as a single-dose injection. When smaller doses are required
the unused portion should be discarded.
Atropine Sulfate Injection is a parenteral
and muscarinic antagonist.
Atropine Sulfate, USP is chemically designated 1a
H, 5a H-Tropan-3-a
ol (±)-tropate(ester), sulfate
(2:1) (salt) monohydrate, (C17H23NO3)2
H2SO4 H2O, colorless crystals or
white crystalline powder very
soluble in water.
Atropine, a naturally occurring belladonna
alkaloid, is a racemic
mixture of equal parts of d- and 1-hyocyamine, whose activity
is due almost entirely to the levo isomer
of the drug.
Sodium Chloride, USP is chemically designated NaCI, a white
crystalline powder freely soluble