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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (F's) » Fluvastatin


Fluvastatin sodium is a water soluble cholesterol lowering agent which acts through the inhibition of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase.

Fluvastatin sodium is [R*, S*-(E)]-(±)-7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6- heptenoic acid, monosodium salt.

This molecular entity is the first entirely synthetic HMG-CoA reductase inhibitor, and is in party structurally distinct from the fungal derivatives of this therapeutic class.

Fluvastatin sodium is a white to pale yellow, hygroscopic powder soluble in water, ethanol and methanol. Lescol is supplied as capsules containing fluvastatin sodium, equivalent to 20 mg or 40 mg of fluvastatin, for oral administration.

Active Ingredient: Fluvastatin sodium

Inactive Ingredients: Gelatin, magnesium stearate, microcrystalline cellulose, pregelatinized starch, red iron oxide, sodium lauryl sulfate, talc, titanium dioxide, yellow iron oxide, and other ingredients.

May also Include: Benzyl alcohol, black iron oxide, butylparaben, carboxymethylcellulose sodium, edetate calcium disodium, methylparaben, propylparaben, silicon dioxide and sodium propionate.


CATEGORIES: Hypercholesterolemia; Hyperlipidemia; Hyperlipoproteinemia; Pregnancy Category X; FDA Class 1S ("Standard Review"); FDA Approved 1993 Dec; Top 200 Drugs

FDA Drug Classes: Hyperlipidemia


BRAND NAMES: Canef; Cranoc; Fractal; Lescol; Locol; Vastin
(Foreign Brand names outside U.S. in italics)

Canef (Mexico)
Cranoc (Germany)
Fractal (France)
Locol (Germany)
Vastin (Australia; New-Zealand)

COST OF THERAPY: $485.45 (Hypercholesterolemia; Lescol Capsule; 20 mg; 1/day; 365 days)

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