Nystatin and Triamcinolone Acetonide Cream for dermatologic use contains
the antifungal agent nystatin and the synthetic corticosteroid triamcinolone
Nystatin is a polyene antimycotic obtained from Streptomyces noursei.
It is a yellow to light tan powder with a cereal-like odor, very slightly
soluble in water, and slightly to sparingly soluble in alcohol.
It has the following empirical formula C47H75NO17
with a molecular weight of 926.13.
Triamcinolone acetonide is designated chemically as 9-fluoro-11b,16a,
17, 21-tetrahydroxypregna -1,4-diene-3,20-dione cyclic 16,17-acetal with
acetone. The white to cream crystalline powder has a slight odor, is practically
insoluble in water, and very soluble in alcohol.
It has the following empirical formula C24H31FO6
with a molecular weight of 434.50.
Nystatin and Triamcinolone Acetonide Cream provides in each gram 100,000
units nystatin and 1 mg triamcinolone acetonide in an aqueous, perfumed
vanishing cream base, containing aluminum hydroxide concentrated wet gel,
titanium dioxide, glyceryl monostearate, polyethylene glycol monostearate,
simethicone emulsion, sorbic acid, propylene glycol, white petrolatum,
cetearyl alcohol (and) ceteareth 20, and sorbitol solution.