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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (O's) » Omeprazole



DESCRIPTION

The active ingredient in Prilosec Delayed-Release Capsules is a substituted benzimidazole, 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole, a compound that inhibits gastric acid secretion. Its empirical formula is C17H19N3O3S, with a molecular weight of 345.42.

Omeprazole is a white to off-white crystalline powder which melts with decomposition at about 155°C. It is a weak base, freely soluble in ethanol and methanol, and slightly soluble in acetone and isopropanol and very slightly soluble in water. The stability of omeprazole is a function of pH; it is rapidly degraded in acid media, but has acceptable stability under alkaline conditions.

Prilosec is supplied as delayed-release capsules for oral administration. Each delayed-release capsule contains either 10 mg or 20 mg of omeprazole in the form of enteric-coated granules with the following inactive ingredients: cellulose, disodium hydrogen phosphate, hydroxypropyl cellulose, hydroxypropyl methylcellulose, lactose, mannitol, sodium lauryl sulfate and other ingredients. The capsule shells have the following inactive ingredients: gelatin-NF, FD&C blue #1, FD&C red #40, D&C red #28, titanium dioxide, synthetic black iron oxide, isopropanol, butyl alcohol, FD&C blue #2, D&C red #7 calcium lake, and, in addition, the 10 mg capsule shell also contains D&C yellow #10.

CATEGORIES, BRAND NAMES

CATEGORIES: Acid/peptic disorder; Adenoma, endocrine; Esophagitis, erosive; Mastocytosis, systemic; Reflux, gastroesophageal; Ulcer, duodenal; Ulcer, gastric; Ulcer, peptic; Zollinger-Ellison syndrome; Pregnancy Category C; FDA Approved 1989 Sep; Top 200 Drugs

FDA Drug Classes: Acid/Peptic Disorders; Gastrointestinal, Miscellaneous

BRAND NAMES:

BRAND NAMES: Acidex; Antra; Audazol; Desec; Dizprazol; Dudencer; Epirazole; Gastroloc; Gibancer; Inhibitron; Inhipump; Logastric; Lomac; Losec; Miracid; Mopral; Ocid; Omed; Omedar; OMEP; Omepril; Omepral; Omeprazon; Omezol; Omezzol; Omid; Omizac; Omisec; OMP; OMZ; Oprax; Opraz; Ozoken; Parizac; Peptilcer; Prazidec; Prilosec; Ramezol; Result; Roweprazol; Ulcozol; Ulsen; Ulzone; Zefxon; Zoltum
(Foreign Brand names outside U.S. in italics)

FOREIGN BRAND AVAILABILITY:
Acidex (Ecuador)
Antra (Germany; Italy; Switzerland)
Audazol (Spain)
Desec (Thailand)
Dizprazol (Colombia)
Dudencer (Indonesia)
Epirazole (Bahrain; Cyprus; Egypt; Iran; Iraq; Jordan; Kuwait; Lebanon; Libya; Oman; Qatar; Republic-of-Yemen; Saudi-Arabia; Syria; United-Arab-Emirates)
Gastroloc (Germany)
Gibancer (Indonesia)
Inhibitron (Mexico)
Inhipump (Indonesia)
Logastric (Belgium)
Lomac (Bahrain; Cyprus; Egypt; India; Iran; Iraq; Jordan; Kuwait; Lebanon; Libya; Oman; Qatar; Republic-of-Yemen; Saudi-Arabia; Syria; United-Arab-Emirates)
Miracid (Thailand)
Mopral (France)
Ocid (Benin; Burkina-Faso; Ethiopia; Gambia; Ghana; Guinea; India; Ivory-Coast; Kenya; Liberia; Malawi; Mali; Mauritania; Mauritius; Morocco; Niger; Nigeria; Senegal; Seychelles; Sierra-Leone; Sudan; Tanzania; Tunia; Uganda; Zambia; Zimbabwe)
Omed (Benin; Burkina-Faso; Ethiopia; Gambia; Ghana; Guinea; India; Ivory-Coast; Kenya; Liberia; Malawi; Mali; Mauritania; Mauritius; Morocco; Niger; Nigeria; Senegal; Seychelles; Sierra-Leone; Sudan; Tanzania; Tunia; Uganda; Zambia; Zimbabwe)
Omedar (Bahrain; Cyprus; Egypt; Iran; Iraq; Jordan; Kuwait; Lebanon; Libya; Oman; Qatar; Republic-of-Yemen; Saudi-Arabia; Syria; United-Arab-Emirates)
OMEP (Germany)
Omepril (Ecuador)
Omepral (Japan)
Omeprazon (Japan)
Omezol (India)
Omezzol (Ecuador)
Omizac (India)
Omisec (Bahrain; Cyprus; Egypt; Iran; Iraq; Jordan; Kuwait; Lebanon; Libya; Oman; Qatar; Republic-of-Yemen; Saudi-Arabia; Syria; United-Arab-Emirates)
OMP (Korea)
OMZ (Indonesia)
Oprax (Peru)
Opraz (Colombia)
Ozoken (Mexico)
Parizac (Spain)
Peptilcer (India)
Prazidec (Mexico)
Ramezol (Korea)
Result (Korea)
Ulcozol (Peru)
Ulsen (Mexico)
Ulzone (Colombia)
Zefxon (Thailand)
Zoltum (France)

COST OF THERAPY: $115.92 (Duodenal Ulcer; Prilosec Capsule; 20 mg; 1/day; 28 days)





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