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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (P's) » Pentazocine and Naloxone


TALWIN® Nx pentazocine and naloxone hydrochlorides, USP Analgesic
for Oral Use Only

TALWIN® Nx is intended for oral use only. Severe, potentially lethal, reactions may result from misuse of TALWIN Nx by injection either alone or in combination with other substances. (See ADVERSE REACTIONS: DRUG ABUSE AND DEPENDENCE subsection.)

TALWIN Nx contains pentazocine hydrochloride, USP, equivalent to 50 mg base and is a member of the benzazocine series (also known as the benzomorphan series), and naloxone hydrochloride, USP, equivalent to 0.5 mg base.

TALWIN Nx is an analgesic for oral administration.

Chemically, pentazocine hydrochloride is 1, 2, 3, 4, 5, 6-Hexahydro-6,11-dimethyl-3-(3- methyl-2-butenyl)-2,6-methano-3-benzazocin-8- ol hydrochloride, a white, crystalline substance soluble in acidic aqueous solutions.

Chemically, naloxone hydrochloride is Morphinan-6-one, 4, 5-epoxy-3, 14-dihydroxy-17- (2-propenyl)-, hydrochloride, (5a). It is a slightly off-white powder, and is soluble in water and dilute acids.

Inactive Ingredients: Colloidal Silicon Dioxide, Dibasic Calcium Phosphate, D&C Yellow #10, FD&C Yellow #6, Magnesium Stearate, Microcrystalline Cellulose, Sodium Lauryl Sulfate, Starch.

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