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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (P's) » Phenytoin



DESCRIPTION

Phenytoin sodium is an antiepileptic drug. Phenytoin sodium is related to the barbiturates in chemical structure, but has a five-membered ring. The chemical name is 5,5-diphenyl-2,4-imidazolidinedione.

Each Dilantin (extended phenytoin sodium) capsule contains 30 mg or 100 mg phenytoin sodium. Also contains lactose, confectioner's sugar, talc, and magnesium stearate. The capsule shell and band contain colloidal silicon dioxide, FD&C red No. 3, gelatin, glyceryl monooleate, sodium lauryl sulfate. The Dilantin 30-mg capsule shell and band also contain citric acid, FD&C blue No. 1, sodium benzoate, titanium dioxide. The Dilantin 100-mg capsule shell and band also contain FD&C yellow No. 6, purified water, and polyethylene glycol 200. Product in vivo performance is characterized by a slow and extended rate of absorption with peak blood concentrations expected in 4-12 hours as contrasted to Prompt Phenytoin Sodium Capsules, with a rapid rate of absorption with peak blood concentration expected in 1 to 3 hours.

CATEGORIES, BRAND NAMES

CATEGORIES: Epilepsy, complex partial; Epilepsy, generalized tonic-clonic; Epilepsy, secondary to neurosurgery; Top 200 Drugs

FDA Drug Classes: Anticonvulsants

BRAND NAMES:

BRAND NAMES: Aleviatin; Antisacer; Cumatil; Difhydan; Di-hydan; Dilantin; Dilantin Kapseals; Dintoina; Diphantoine; Diphantoine-Z; Diphen; Diphentoin; Diphenylan Sodium; Ditoin; Ditomed; Dyatoin; Epamin; Epanutin; Epilan-D; Epilantin; Epileptin; Eptoin; Fenatoin NM; Fenidantoin S 100; Fenitron; Fenytoin; Hidanil; Hydantin; Hydantol; Lehydan; Nuctane; Phenhydan; Phenilep; Phenytoin KP; Phenytex; Prompt Phenytoin Sodium; Pyoredol

FOREIGN BRAND AVAILABILITY:
Aleviatin (Japan)
Antisacer (Portugal)
Cumatil (Colombia)
Difhydan (Denmark)
Di-hydan (France)
Dintoina (Italy)
Diphantoine (Belgium)
Diphantoine-Z (Netherlands)
Ditoin (Malaysia; Thailand)
Ditomed (Thailand)
Epamin (Argentina; Canada; CIS; Colombia; Ecuador; Mexico; Peru)
Epanutin (Austria; Bahrain; Belgium; Benin; Burkina-Faso; Cyprus; Egypt; England; Ethiopia; Finland; Gambia; Germany; Ghana; Greece; Guinea; Hungary; Iran; Iraq; Ireland; Israel; Ivory-Coast; Jordan; Kenya; Kuwait; Lebanon; Liberia; Libya; Malawi; Mali; Mauritania; Mauritius; Morocco; Netherlands; Niger; Nigeria; Oman; Qatar; Republic-of-Yemen; Saudi-Arabia; Senegal; Seychelles; Sierra-Leone; South-Africa; Spain; Sudan; Sweden; Switzerland; Syria; Tanzania; Tunia; Turkey; Uganda; United-Arab-Emirates; Zambia; Zimbabwe)
Epilan-D (Austria)
Epilantin (Switzerland)
Epileptin (India; Taiwan)
Eptoin (India)
Fenatoin NM (Sweden)
Fenidantoin S 100 (Mexico)
Fenitron (Mexico)
Fenytoin (Denmark; Germany)
Hidanil (Colombia)
Hydantin (Finland)
Hydantol (Japan)
Lehydan (Sweden)
Nuctane (Mexico)
Phenhydan (Austria; Germany; Switzerland)
Phenilep (Indonesia)
Phenytoin KP (Thailand)
Pyoredol (Argentina)

COST OF THERAPY: $525.60 (Epilepsy; Dilantin Capsule; 50 mg; 6/day/day; 365 days)

HCFA JCODE(S): J1165 per 50 mg IM, IV





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