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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (P's) » Podofilox


Podofilox is an antimitotic drug which can be chemically synthesized or purified from the plant families Coniferae and Benberidaceae (e.g. species of Juniperus and Podophyllum). Condylox® Gel 0.5% is formulated for topical administration. Each gram of gel contains 5mg of podofilox in a buffered alcoholic gel containing alcohol, glycerin, lactic acid, hydroxypropyl cellulose, sodium lactate, and butylated hydroxytoluene.

Podofilox has a molecular weight of 414.4 daltons, and is soluble in alcohol and sparingly soluble in water. Its chemical name is [5R(5a,5a13,8aa,9cx]-5,8,8a,9-tetrahydro-9-hydroxy-5-(3,4,5- trimethoxyphenyl) furo[3,4: 6,7] naphtho-[2,3,-d]-1,3-dioxol-6(5aH) one.

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