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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (F's) » Felodipine


Plendil (felodipine) is a calcium antagonist (calcium channel blocker). Felodipine is a dihydropyridine derivative that is chemically described as ± ethyl methyl 4-(2,3 -dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate. Its empirical formula is C18H19Cl2NO4.

Felodipine is a slightly yellowish, crystalline powder with a molecular weight of 384.26. It is insoluble in water and is freely soluble in dichloromethane and ethanol. Felodipine is a racemic mixture.

Felodipine tablets provide extended release of felodipine. They are available as tablets containing 2.5 mg, 5 mg or 10 mg of felodipine for oral administration. In addition to the active ingredient felodipine, the tablets contain the following inactive ingredients: felodipine 2.5 mg ¾ hydroxypropyl cellulose, lactose, FD&C blue 2, sodium stearyl fumarate, titanium dioxide, yellow iron oxide and other ingredients. Felodipine 5 mg and 10 mg ¾ cellulose, red and yellow oxide, lactose, polyethylene glycol, sodium stearyl fumarate, titanium dioxide and other ingredients.


CATEGORIES: Hypertension, essential; Pregnancy Category C; FDA Class 1C ("Little or No Therapeutic Advantage"); FDA Approved 1991 Jul; Top 200 Drugs

FDA Drug Classes: Antihypertensives; Calcium Channel Blockers


BRAND NAMES: AGON SR; Felodur ER; Felogard; Flodil LP; Hydac; Modip; Munobal; Munobal Retard; Penedil; Plendil; Plendil Depottab; Plendil ER; Plendil Retard; Renedil; Splendil; Splendil ER
(Foreign Brand names outside U.S. in italics)

AGON SR (Australia; New-Zealand)
Felodur ER (Australia)
Felogard (Bahrain; Cyprus; Egypt; India; Iran; Iraq; Jordan; Kuwait; Lebanon; Libya; Oman; Qatar; Republic-of-Yemen; Saudi-Arabia; Syria; United-Arab-Emirates)
Flodil LP (France)
Hydac (Denmark; Finland; Sweden)
Modip (Germany)
Munobal (Germany; Japan; Mexico; Philippines; Thailand)
Munobal Retard (Austria; Germany; Switzerland)
Penedil (Israel)
Plendil Depottab (Norway)
Plendil ER (Australia; New-Zealand; Philippines)
Plendil Retard (Austria)
Renedil (Belgium; Canada; India)
Splendil (Japan)
Splendil ER (Korea)

COST OF THERAPY: $361.35 (Hypertension; Plendil Tablet; 5 mg; 1/day; 365 days)

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