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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (i's) » Indapamide


Indapamide is an oral antihypertensive/diuretic. Its molecule contains both a polar sulfamoyl chlorobenzamide moiety and a lipid- soluble methylindoline moiety. It differs chemically from the thiazides in that it does not possess the thiazide ring system and contains only one sulfonamide group. The chemical name of indapamide is 4-Chloro-N-(2-methyl-1- indolinyl)-3-Sulfamoylbenzamide, and its molecular weight is 365. 84. The compound is a weak acid, pKa= 8.8, and is soluble in aqueous solutions of strong bases. It is a white to yellow-white crystalline (tetragonal) powder.

Each tablet, for oral administration, contains 1.25 mg or 2.5 mg of indapamide. In addition, each tablet contains the following inactive ingredients: corn starch, hydroxypropyl methylcellulose, lactose monohydrate, magnesium stearate, maltodextrin, microcrystalline cellulose, polydextrose polyethylene glycol, talc, titanium dioxide, triacetin. The 1.25 mg tablet also contains FD& C yellow #6 aluminum lake (sunset yellow lake).

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