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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (i's) » Insulin (Human Recombinant)



DESCRIPTION

Humulin is synthesized in a special non-disease-producing special laboratory strain of Escherichia coli bacteria that has been genetically altered by the addition of the gene for human insulin production.

Humulin R consists of zinc-insulin crystals dissolved in a clear fluid. Humulin R has nothing added to change the speed or length of its action. It takes effect rapidly and has a relatively short duration of activity (4 to 12 hours) as compared with other insulins.

Humulin N is a crystalline suspension of human insulin with protamine and zinc providing an intermediate-acting insulin with a slower onset of action and a longer duration of activity (up to 24 hours) than that of regular insulin.

Humulin L is an amorphous and crystalline suspension of human insulin with a slower onset and a longer duration of activity (up to 24 hours) than regular insulin.

Humulin U is a crystalline suspension of human insulin with zinc providing a slower onset and a longer and less intense duration of activity (up to 28 hours) than regular insulin or the intermediate-acting insulins (NPH and Lente).

Humulin 50/50 is a mixture of 50% Human Insulin Isophane Suspension and 50% Human Insulin Injection. It is an intermediate-acting insulin combined with the more rapid onset of action than regular insulin. The duration of activity may last up to 24 hours following injection.

Humulin 70/30 is a mixture of 70% Human Insulin Isophane Suspension and 30% Human Insulin Injection. It is an intermediate-acting insulin combined with the more rapid onset of action of regular insulin. The duration of activity may last up to 24 hours following injection.

The time course of action of any insulin may vary considerably in different individuals or at different times in the same individual. As with all insulin preparation, the duration of action of all forms of Humulin is dependent on dose, site of injection, blood supply, temperature, and physical activity. Humulin is a sterile solution and is for subcutaneous injection. It should not be used intravenously or intramuscularly. The concentration of all forms of Humulin is 100 units/ml (U-100).

CATEGORIES, BRAND NAMES

HUMULIN

CATEGORIES: Diabetes Mellitus; Recombinant DNA Origin; FDA Approved 1982 Oct; Top 200 Drugs

FDA Drug Class: Blood Glucose Regulators

BRAND NAMES: Actrapid; Actrapid HM; Actrapid Human; Berlinsulin Actrapid Normal U-40; Berlinsulin H Basal U-40; Human Actrapid; Human Nordisulin; Huminsulin "Lilly" Normal; Huminsulin Normal; Humulin; Humulina Regular; Humulin Br; Humulin C; Humulin R; Humulin-R; Humulin Regular; Humulin (Regular); Humuline Regular; Insulina; Insulina Actrapid HM; Insulina Velosulin HM; Insulin Hoechst-Rapid U-100; Insulin Human; Insulin Human Actrapid; Insulin Actrapid HM; Insulin "Novo Nordisk" Actrapid HM; Insulin "Novo Nordisk" Velosulin HM; Insulin Velosulin HM; Insuline; Insuline Actrapid; Insuline Humuline Regular; Insuline Velosulin Humaan; Insuman; Mixtard Human 70 30; Novolin 70 30 Penfill; Novolin N Penfill; Novolin R; Novolin-Toronto; Velosulin; Velosulin Human; Velosulin Human R; Velosuline Humaine
(Foreign brand names outside U.S. in italics)

HUMULIN 70 30

CATEGORIES: Diabetes Mellitus; Recombinant DNA Origin; FDA Pre 1938; Top 200 Drugs

FDA Drug Class: Blood Glucose Regulators

BRAND NAMES: Actraphane HM; Berlinsulin H 10 90; Berlinsulin H 20 80; Berlinsulin H 30 70; Berlinsulin H 40 60; Human Actraphane; Huminsulin "Lilly" Long; Huminsulin Profil I; Huminsulin Profil II; Huminsulin Profil III; Huminsulin Profil IV; Humulin 10 90; Humulin 20 80; Humulin 30 70; Humulin 40 60; Humulin 50 50; Humulin 60 40; Humulin 70 30; Humulin 80 20; Humulin 90 10; Humulin M3; Humulin M2; Humulin M1; Humulin M4; Humulina 10 90; Humulina 20 80; Humulina 30 70; Humulina 40 60; Humulina 50 50; Humulina 70 30; Humuline 20 80; Humuline 30 70; Humuline 40 60; Insulin Actraphan HM; Insulin Actraphane HM; Insulin Actraphane HM 30 70; Insulin Actraphane HM 10 90; Insulin Actraphane HM 20 80; Insulin Actraphane HM 40 60; Insulin Actraphane HM 50 50; Insulin Hoechst-Komb 15 U-100; Insulin Hoechst-Komb 25 U-100; Insulin Hoechst-Komb 50 U-100; Insulin Mixtard 10 HM; Insulin Mixtard 20 HM; Insulin Mixtard 30 HM; Insulin Mixtard 40 HM; Insulin Mixtard 50 HM; Insulin Mixtard 50 50 HM; Insulin Mixtard 30 70 Human; Insulin Mixtard 50 50 Human; Insulin Mixtard 15 85 Human; Insulin Mixtard Human; Insulin "Novo Nordisk" Mixtard HM 15 85; Insulin "Novo Nordisk" Mixtard HM 30 70; Insulin "Novo Nordisk" Mixtard HM 50 50; Insulina Combi HM 85 15; Insulina Mixt HM 30 70; Insuline Humaan; Insuline Humuline 10 90; Insuline Humuline 20 80; Insuline Humuline 30 70; Insuline Humuline 40 60; Mixtard 15 85; Mixtard 20 80; Mixtard 30 70; Mixtard 30 HM; Mixtard 50 50; Mixtard Human; Mixtard 30 Human; Novolet 30 70; Novolin 30 70; Novolin 70 30; Umuline Profil 10; Umuline Profil 20; Umuline Profil 30; Umuline Profil 40
(Foreign brand names outside U.S. in italics)

HUMULIN N

CATEGORIES: Diabetes Mellitus; Recombinant DNA Origin; FDA Pre1938; Top 200 Drugs

FDA Drug Class: Blood Glucose Regulators

BRAND NAMES: Basal-H-Insulin; Human Insulatard; Human Protaphane; Huminsulin Basal (NPH); Huminsulin "Lilly" Basal (NPH); Humulin I; Humulin N; Humulin NPH; Humulina NPH; Humuline NPH; Insulatard; Insulatard HM; Insulatard Human; Insulatard NPH Human; Insulin Human; Insulin Insulatard HM; Insulin Insulatard Human; Insulin "Novo Nordisk" Insulatard HM; Insulin Protaphane HM; Insuline; Insuline Humuline NPH; Insuline Isuhuman Basal; Insuline Insulatard; Novolin N; Novolin NPH; Protaphane; Protaphane HM
(Foreign brand names outside U.S. in italics)





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