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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (i's) » Ipratropium Bromide (inhalation)



DESCRIPTION

The active ingredient in Atrovent (ipratropium bromide) is ipratropium bromide monohydrate. It is an anticholinergic bronchodilator chemically described as 8-azoniabicyclo(3.2.1)-octane,3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1-methylethyl)-,bromide, monohydrate(endo, syn)-, (±)-; a synthetic quaternary ammonium compound, chemically related to atropine.

Ipratropium bromide is a white to off-white crystalline substance, freely soluble in water and lower alcohols. It is a quaternary ammonium compound and thus exists in an ionized state in aqueous solutions. It is relatively insoluble in non-polar media.

Atrovent Inhalation Aerosol is an inhalation aerosol for oral administration. The net weight is 14 grams; it yields 200 inhalations. Each actuation of the valve delivers 18 mcg of ipratropium bromide from the mouthpiece. The inert ingredients are dichlorodifluoromethane, dichlorotetrafluoroethane, and trichlorofluoromethane as propellants and soya lecithin.

Atrovent Inhalation Solution is administered by oral inhalation with the aid of a nebulizer. It contains ipratropium bromide 0.02% (anhydrous basis) in a sterile, preservative-free, isotonic saline solution, pH-adjusted to 3.4 (3 to 4) with hydrochloric acid.

CATEGORIES, BRAND NAMES

CATEGORIES: Bronchitis, chronic; Emphysema; FDA Approved 1986 Dec; Pregnancy Category B; Top 200 Drugs

FDA Drug Classes: Antiasthmatics

BRAND NAMES:

BRAND NAMES: Aerovent; Apovent; Atem; Atronase; Atrovent; Atrovent Aerosol; Atrovent Nasal; Disne-Asmol; Ipravent; Ipvent; Narilet; Tropium
(Foreign Brand names outside U.S. in italics)

FOREIGN BRAND AVAILABILITY:
Aerovent (Bahrain; Cyprus; Egypt; Iran; Iraq; Israel; Israel; Jordan; Kuwait; Lebanon; Libya; Oman; Qatar; Republic-Of-Yemen; Saudi-Arabia; Syria; United-Arab-Emirates)
Apovent (Israel)
Atem (Italy)
Atronase (Belgium)
Atrovent Aerosol (Australia; New-Zealand; New-Zealand)
Atrovent Nasal (Australia; Hong-Kong; New-Zealand; New-Zealand)
Ipravent (India)
Ipvent (South-Africa)
Narilet (Spain)
Tropium (Costa-Rica; Dominican-Republic; El-Salvador; Guatemala; Honduras; Nicaragua; Panama)

HCFA JCODE(S): J7645 per ml INH





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