Latanoprost is a prostaglandin
F2a analogue. Its chemical
name is isopropyl-(Z)-7[(1R, 2R, 3R, 5S)3, 5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-5-heptenoate.
Its molecular formula
is C26H40O5 and its molecular weight
Latanoprost is a colorless to slightly yellow
oil which is very soluble
and freely soluble in
acetone, ethanol, ethyl
acetate, isopropanol, methanol, and octanol. It is practically insoluble
Xalatan sterile ophthalmic
solution is supplied
as sterile, isotonic, buffered aqueous
solution of latanoprost
with a pH of approximately
6.7 and an osmolality of approximately 267 mOsmol/kg. Each ml
of Xalatan contains 50 mg of latanoprost.
Benzalkonium chloride, 0.02% is added as a preservative. Inactive
Ingredients: Sodium chloride, sodium dihydrogen phosphate
monohydrate, disodium hydrogen
and water for injection.
One drop contains approximately
1.5 mg of latanoprost.
CATEGORIES, BRAND NAMES
CATEGORIES: Glaucoma, open-angle; Hypertension, ocular;
Pregnancy Category C; FDA Approved 1996 Aug; Top 200 Drugs
FDA Drug Classes: Glaucoma
BRAND NAMES: Xalatan