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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (L's) » Latanoprost


Latanoprost is a prostaglandin F2a analogue. Its chemical name is isopropyl-(Z)-7[(1R, 2R, 3R, 5S)3, 5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-5-heptenoate. Its molecular formula is C26H40O5 and its molecular weight is 432.58.

Latanoprost is a colorless to slightly yellow oil which is very soluble in acetonitrile and freely soluble in acetone, ethanol, ethyl acetate, isopropanol, methanol, and octanol. It is practically insoluble in water.

Xalatan sterile ophthalmic solution is supplied as sterile, isotonic, buffered aqueous solution of latanoprost with a pH of approximately 6.7 and an osmolality of approximately 267 mOsmol/kg. Each ml of Xalatan contains 50 mg of latanoprost. Benzalkonium chloride, 0.02% is added as a preservative. Inactive Ingredients: Sodium chloride, sodium dihydrogen phosphate monohydrate, disodium hydrogen phosphate anhydrous, and water for injection. One drop contains approximately 1.5 mg of latanoprost.


CATEGORIES: Glaucoma, open-angle; Hypertension, ocular; Pregnancy Category C; FDA Approved 1996 Aug; Top 200 Drugs

FDA Drug Classes: Glaucoma



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