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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (M's) » Methyldopate HCl


Methyldopate HCl Injection, USP, is an antihypertensive agent for intravenous use. Sterile, nonpyrogenic. Methyldopate hydrochioride [levo-3-(3,4-dihydroxyphenyl)-2-methylalanine, ethyl ester hydrochloride] is the ethyl ester of methyldopa, supplied as the hydrochloride salt with a molecular weight of 275.73. Methyldopate hydrochloride is more soluble and stable in solution than methyldopa and is the preferred form for intravenous use.

The molecular formula for Methyldopate hydrochloride is C12H17NO4HCl.

Each mL contains:

Methyldopate Hydrochloride 50 mg
Citric Acid (Anhydrous) 5 mg
Edetate Disodium 0.5 mg
Monothioglycerol 2 mg
Water for Injection q. s. to 1 mL

Methylparaben 1.5 mg and Propylparaben 0.2 mg added as preservatives, Sodium Bisulfite 3.2 mg added as an antioxidant, pH adjusted with Sodium Hydroxide and/or Hydrochloric Acid.

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