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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (M's) » Mexiletine HCl


Mexitil® (mexiletine hydrochloride, USP) is an orally active antiarrhythmic agent available as 150 mg, 200 mg and 250 mg capsules. 100 mg of mexiletine hydrochloride is equivalent to 83.31 mg of mexiletine base. It is a white to off-white crystalline powder with slightly bitter taste, freely soluble in water and in alcohol. Mexitil® has a pKa of 9.2.

Chemically, Mexitil® is 1-methyl-2-(2,6-xylyloxy) ethylamine hydrochloride. It has the following molecular formula C11H17NOHCl with a molecular weight of 215.73.

Mexitil® Capsules contain the following inactive ingredients: colloidal silicon dioxide, corn starch, magnesium stearate, titanium dioxide, gelatin, FD&C Red No. 40, D&C Red No. 28 and FD&C Blue No. 1; the Mexitil® 150 mg and 250 mg capsule also contain FD&C Yellow No. 6. Mexitil capsules may contain one or more of the following components: sodium lauryl sulfate, sodium proprionate, edetate calcium disodium, benzyl alcohol, carboxymethylcellulose sodium, glycerin, butylparaben, propylparaben, methylparaben, pharmaceutical glaze, ethylene glycol monoethylether, soya lecithin, dimethylpolysiloxafle, refined shellac (food grade) and other inactive ingredients.

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