DESCRIPTION

The active ingredient in Pepcid is a histamine H₂-receptor antagonist. Famotidine is N'-(aminosulfonyl)-3-[[[2- [(diaminomethylene)amino]-4-thiazolyl]methyl]thio]propanimidamide. The empirical formula of famotidine is C₈H₁₅N₇O₂S₃ and its molecular weight is 337.43.

Famotidine is a white to pale yellow crystalline compound that is freely soluble in glacial acetic acid, slightly soluble in methanol, very slightly soluble in water, and practically insoluble in ethanol.

Each tablet for oral administration contains either 20 mg or 40 mg of famotidine. Inactive Ingredients: Hydroxypropyl cellulose, hydroxypropyl methylcellulose, iron oxides, magnesium stearate, microcrystalline cellulose, starch, talc, titanium dioxide.

Each Pepcid RPD orally disintegrating tablet for oral administration contains either 20 mg or 40 mg of famotidine and the following inactive ingredients: aspartame, mint flavor, gelatin, mannitol, red ferric oxide, and xanthan gum.

Each 5 ml of the oral suspension when prepared as directed contains 40 mg of famotidine and the following inactive ingredients: citric acid, flavors, microcrystalline cellulose and carboxymethylcellulose sodium, sucrose and xanthan gum. Added as preservatives are sodium benzoate 0.1%, sodium methylparaben 0.1%, and sodium propylparaben 0.02%.

Each ml of the solution for intravenous injection contains 10 mg of famotidine. Inactive Ingredients: L-aspartic acid 4 mg, mannitol 20 mg, and Water for Injection q.s. 1 ml. The multidose injection also contains benzyl alcohol 0.9% added as preservative.

CATEGORIES, BRAND NAMES

CATEGORIES: Acid/peptic disorder; Adenoma, secretory; Reflux, gastroesophageal; Ulcer, duodenal; Ulcer, gastric; Zollinger-Ellison syndrome; Pregnancy Category B; FDA Approved 1986 Oct; Top 200 Drugs

FDA Drug Classes: Acid/Peptic Disorders

BRAND NAMES:

BRAND NAMES: Amfamox; Antodine; Apo-Famotidine; Apogastine; Bestidine; Brolin; Cepal; Dibrit 40; Durater; Evatin; Facid; Fadin; Fadine; Fadyn; Fagastine; Famo; Famocid; Famodar; Famodil; Famodin; Famodine; Famogard; Famonit; Famopsin; Famos; Famosan; Famotal; Famotep; Famotin; Famotine; Famovane; Famowal; Famox; Famoxal; Fanox; Farmotex; Fenox; Ferotine; Fibonel; Fudone; Ganor; Gaster; Gastridin; Gastrion; Gastro; Gastrodomina; Hacip; H2 Bloc; Logos; Mosul; Motiax; Neocidine; Panalba; Pepcid; Pepcid AC; Pepcidac; Pepcidin; Pepcidin Rapitab; Pepcidina; Pepcidine; Pepdif; Pepdine; Pepdul; Pepfamin; Peptan; Peptidin; Peptifam; Pepzan; Purifam; Quamatel; Quamtel; Restadin; Rogasti; Sedanium-R; Sigafam; Supertidine; Tamin; Topcid; Ulcatif; Ulceran; Ulcofam; Ulfagel; Ulfam; Ulfinol; Ulgarine; Weimok; Whitidin; Yamarin
(Foreign Brand names outside U.S. in italics)

FOREIGN BRAND AVAILABILITY:
Amfamox (Australia; New-Zealand)
Antodine (Bahrain; Cyprus; Egypt; Iran; Iraq; Israel; Jordan; Kuwait; Lebanon; Libya; Oman; Qatar; Republic-Of-Yemen; Saudi-Arabia; Syria; United-Arab-Emirates)
Apo-Famotidine (New-Zealand)
Apogastine (Israel)
Bestidine (Korea)
Brolin (Spain)
Cepal (Greece)
Dibrit 40 (Colombia)
Durater (Mexico)
Evatin (Korea)
Facid (India; Indonesia)
Fadin (Taiwan)
Fadine (Malaysia; Thailand)
Fadyn (Colombia)
Fagastine (Korea)
Famo (Israel)
Famocid (Benin; Burkina-Faso; Ethiopia; Gambia; Ghana; Guinea; India; Ivory-Coast; Kenya; Liberia; Malawi; Mali; Mauritania; Mauritius; Morocco; Niger; Nigeria; Senegal; Seychelles; Sierra-Leone; South-Africa; Sudan; Tanzania; Tunia; Uganda; Zambia; Zimbabwe)
Famodar (Bahrain; Cyprus; Egypt; Iran; Iraq; Israel; Jordan; Kuwait; Lebanon; Libya; Oman; Qatar; Republic-Of-Yemen; Saudi-Arabia; Syria; United-Arab-Emirates)
Famodil (Italy)
Famodin (Bulgaria)
Famodine (Bahrain; Cyprus; Egypt; Iran; Iraq; Israel; Jordan; Kuwait; Lebanon; Libya; Oman; Qatar; Republic-Of-Yemen; Saudi-Arabia; Syria; United-Arab-Emirates)
Famogard (Russia)
Famonit (Benin; Burkina-Faso; Ethiopia; Gambia; Ghana; Guinea; India; Ivory-Coast; Kenya; Liberia; Malawi; Mali; Mauritania; Mauritius; Morocco; Niger; Nigeria; Senegal; Seychelles; Sierra-Leone; South-Africa; Sudan; Tanzania; Tunia; Uganda; Zambia; Zimbabwe)
Famopsin (Hong-Kong; Malaysia; Thailand)
Famos (Indonesia)
Famosan (Bulgaria)
Famotal (Norway)
Famotep (Portugal)
Famotin (Ecuador)
Famotine (Peru)
Famovane (India)
Famowal (India)
Famox (Hong-Kong; New-Zealand; Taiwan)
Famoxal (Mexico)
Fanox (Spain)
Farmotex (Mexico)
Fenox (Colombia)
Ferotine (Korea)
Fibonel (Ecuador)
Fudone (Benin; Burkina-Faso; Ethiopia; Gambia; Ghana; Guinea; Ivory-Coast; Kenya; Liberia; Malawi; Mali; Mauritania; Mauritius; Morocco; Niger; Nigeria; Senegal; Seychelles; Sierra-Leone; Sudan; Tanzania; Tunia; Uganda; Zambia; Zimbabwe)
Ganor (Germany)
Gaster (Japan; Taiwan)
Gastridin (Italy)
Gastrion (Spain)
Gastro (Israel)
Gastrodomina (Benin; Burkina-Faso; Ethiopia; Gambia; Ghana; Guinea; Ivory-Coast; Kenya; Liberia; Malawi; Mali; Mauritania; Mauritius; Morocco; Niger; Nigeria; Senegal; Seychelles; Sierra-Leone; South-Africa; Sudan; Tanzania; Tunia; Uganda; Zambia; Zimbabwe)
Hacip (Indonesia)
H2 Bloc (Philippines)
Logos (South-Africa)
Mosul (Indonesia)
Motiax (Italy)
Neocidine (Costa-Rica; Dominican-Republic; El-Salvador; Guatemala; Honduras; Nicaragua; Panama)
Panalba (Greece; Russia)
Pepcid AC (New-Zealand)
Pepcidac (France)
Pepcidin (Denmark; Finland; Netherlands; Norway; Sweden; Turkey)
Pepcidin Rapitab (Norway)
Pepcidina (Portugal)
Pepcidine (Australia; Austria; Belgium; Colombia; Costa-Rica; Ecuador; El-Salvador; Guatemala; Honduras; Hong-Kong; Malaysia; Mexico; New-Zealand; New-Zealand; Nicaragua; Panama; Philippines; Russia; Switzerland)
Pepdif (Turkey)
Pepdine (Benin; Burkina-Faso; Ethiopia; France; Gambia; Ghana; Guinea; Ivory-Coast; Kenya; Liberia; Malawi; Mali; Mauritania; Mauritius; Morocco; Niger; Nigeria; Senegal; Seychelles; Sierra-Leone; South-Africa; Sudan; Tanzania; Tunia; Uganda; Zambia; Zimbabwe)
Pepdul (Germany)
Pepfamin (Thailand)
Peptan (Greece)
Peptidin (Korea)
Peptifam (Bahrain; Cyprus; Egypt; Iran; Iraq; Israel; Jordan; Kuwait; Lebanon; Libya; Oman; Qatar; Republic-Of-Yemen; Saudi-Arabia; Syria; United-Arab-Emirates)
Pepzan (Hong-Kong; New-Zealand; Thailand)
Purifam (Indonesia)
Quamatel (Hong-Kong)
Quamtel (Bahamas; Barbados; Belize; Bermuda; Curacao; Guyana; Jamaica; Netherland-Antilles; Puerto-Rico; Surinam; Trinidad)
Restadin (Indonesia)
Rogasti (Israel)
Sedanium-R (Greece)
Sigafam (Mexico)
Supertidine (Taiwan)
Tamin (Spain)
Topcid (India)
Ulcatif (Bahrain; Cyprus; Egypt; Iran; Iraq; Jordan; Kuwait; Lebanon; Libya; Oman; Qatar; Republic-Of-Yemen; Saudi-Arabia; Syria; United-Arab-Emirates)
Ulceran (Bahrain; Cyprus; Egypt; Hong-Kong; Iran; Iraq; Israel; Jordan; Kuwait; Lebanon; Libya; Malaysia; Oman; Qatar; Republic-Of-Yemen; Saudi-Arabia; Syria; United-Arab-Emirates)
Ulcofam (Thailand)
Ulfagel (Colombia; Ecuador)
Ulfam (Indonesia)
Ulfinol (Costa-Rica; Dominican-Republic; El-Salvador; Guatemala; Honduras; Nicaragua; Panama)
Ulgarine (Costa-Rica; Dominican-Republic; El-Salvador; Honduras; Panama)
Weimok (Taiwan)
Whitidin (Korea)
Yamarin (Benin; Burkina-Faso; Ethiopia; Gambia; Ghana; Guinea; Ivory-Coast; Kenya; Liberia; Malawi; Mali; Mauritania; Mauritius; Morocco; Niger; Nigeria; Senegal; Seychelles; Sierra-Leone; Sudan; Tanzania; Tunia; Uganda; Zambia; Zimbabwe)

COST OF THERAPY: $99.68 (Duodenal Ulcer; Pepcid Tablet; 40 mg; 1/day; 28 days)