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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (F's) » Fluorouracil



DESCRIPTION

ADRUCIL® Injection (fluorouracil injection, USP), an antineoplastic antimetabolite, is a colorless to faint yellow aqueous, sterile, nonpyrogenic injectable solution for intravenous administration. Each 10 mL contains 500 mg of fluorouracil; pH is adjusted to 8.6 to 9.4 with sodium hydroxide and hydrochloric acid if necessary.

Chemically, fluorouracil, a fluorinated pyrimidine, is 5-fluoro-2,4(1H,3H)-pyrimidinedione. It is a white to practically white crystalline powder which is sparingly soluble in water. It has molecular formula C4H3FN2O2 with a molecular weight of 130.08.





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