About UsContact UsFAQsView Our NewsletterHiringTrack OrderView Cart MY ACCOUNT Ph no: (609) 848-8890
Shop with Confidence
Yahoo Shopping 5 Star- Top service Site
Email this page to your friends
Subscribe to our Newsletter!

Translate This Page:

Mastercard Visa Discover JCB

Go Daddy $1.99 Domains
You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (N's) » Nitroprusside Sodium



After reconstitution with appropriate diluent, NITROPRESS (Sodium Nitroprusside Injection) is not suitable for direct injection. The reconstituted solution must be further diluted in sterile 5% dextrose injection before infusion.

NITROPRESS can cause precipitous decreases in blood pressure (see DOSAGE AND ADMINISTRATION). In patients not properly monitored, these decreases can lead to irreversible ischemic injuries or death. Sodium nitroprusside should be used only when available equipment and personnel allow blood pressure to be continuously monitored.

Except when used briefly or at low (< 2 pg/kg/min) infusion rates, sodium nitroprusside gives rise to important quantities of cyanide ion, which can reach toxic, potentially lethal levels (see WARNINGS). The usual dose rate is 0.5-10 pg/kg/mm, but infusion at the maximum dose rate should never last more than 10 minutes. If blood pressure has not been adequately controlled after 10 minutes of infusion at the maximum rate, administration of sodium nitroprusside should be terminated immediately.

Although acid-base balance and venous oxygen concentration should be monitored and may indicate cyanide toxicity, these laboratory tests provide imperfect guidance.

This information should be thoroughly reviewed before administration of NITROPRESS. 

Sodium nitroprusside is disodium pentacyanonitrosylferrate(2-) dihydrate, an inorganic hypotensive agent whose molecular formula is Na2[Fe(CN)5NO] 2H2O, and whose molecular weight is 297.95. Dry sodium nitroprusside is a reddish-brown powder, soluble in water. In an aqueous solution infused intravenously, sodium nitroprusside is a rapid-acting vasodilator, active on both arteries and veins.

Sodium nitroprusside solution is rapidly degraded by trace contaminants, often with resulting color changes. (See DOSAGE AND ADMINISTRATION section.) The solution is also sensitive to certain wavelengths of light, and it must be protected from light in clinical use.

NITROPRESS (Sodium Nitroprusside Injection) is available as:

50 mg Fliptop Vial Each 2 mL vial contains the equivalent of 50 mg sodium nitroprusside dihydrate in sterile water for injection.

Contact UsBrochure RequestShipping & ReturnsPrivacy PolicySite MapCompany InformationView Shopping Cart
eGeneralMedical.com™ and the contents of this site are Trademark and Copyright protected – All rights reserved 2000-2010.
Ordering Help
Shipping & Returns Help
Partner With Us
Our Policies
Contact the Webmaster with any questions regarding the content of this website.

eGeneralMedical.com - Health Care Supplies, Medical Equipment, Alternative Health,Stethoscopes, Blood Pressure Monitors, Scales/Body Fat Monitors, Diabetic Supplies, Air Purifiers, White Noise Machines, Vitamins, Massage/Spa., Medical PDA Software