NOROXIN (Norfloxacin) is a synthetic, broad-spectrum antibacterial agent
for oral administration. Norfloxacin, a fluoroquinolone, is 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic
acid. Its empirical formula is C16H18FN3O3.
Norfloxacin is a white to pale yellow crystalline powder with a molecular
weight of 319.34 and a melting point of about 221 C. It is freely soluble
in glacial acetic acid, and very slightly soluble in ethanol, methanol
NOROXIN is available in 400-mg tablets. Each tablet contains the following
inactive ingredients: cellulose, croscarmellose sodium, hydroxypropyl
cellulose, hydroxypropyl methylcellulose, iron oxide, magnesium stearate,
and titanium dioxide.
Norfloxacin, a fluoroquinolone, differs from non-fluorinated quinolones
by having a fluorine atom at the 6 position and a piperazine moiety at
the 7 position.