DESCRIPTION

Prazosin hydrochloride, a quinazoline derivative, is the first of a new chemical class of antihypertensives. It is the hydrochloride salt of 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furoyl) piperazine.

It has the following molecular formula C₁₉H₂₁N₅O₄HCl.

It is a white to tan powder, slightly soluble in water and methanol, very slightly soluble in alcohol, practically insoluble in chloroform and acetone, and has a molecular weight of 419.87. Each capsule for oral administration contains prazosin hydrochloride (anhydrous) equivalent to 1mg, 2mg, or 5mg of prazosin and contains the following inactive ingredients: Corn Starch, Gelatin, Magnesium Stearate, Sucrose, and Titanium Dioxide. In addition, the 1mg capsules contain Red 40; the 2mg capsules contain Blue 1, Red 28 and Red 40; and the 5mg capsules contain Blue 1 and Red 28.