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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (S's) » Selegiline



DESCRIPTION

Selegiline hydrochloride is a levorotatory acetylenic derivative of phenethylamine. It is commonly referred to in the clinical and pharmacological literature as L-deprenyl.

The chemical name is: (R)-(-)-N,2-dimethyl-N-2- propynylphenethylamine hydrochloride. It is a white to near white crystalline powder, freely soluble in water, chloroform, and methanol. The molecular formula is C13H17N·HCl and has a molecular weight of 223.75.

Each Eldepryl white, shield shaped, unscored tablet, debossed on one side with "S" and "5" on the other side, contains 5 mg selegiline hydrochloride. Inactive ingredients are citric acid, lactose, magnesium stearate, and microcrystalline cellulose.

Each Carbex tablet for oral administration contains 5 mg selegiline hydrochloride and the following inactive ingredients: corn starch, lactose monohydrate, magnesium stearate, povidone, and talc.

CATEGORIES, BRAND NAMES

CATEGORIES: Extrapyramidal Movement Disorders; Parkinsonism; Pregnancy Category C; FDA Approved 1989 Jun; Orphan Drugs

FDA Drug Class: Extrapyramidal Movement Disorders

BRAND NAMES: Alzene; Carbex; Deprenyl; Eldeprine; Eldepryl; Jumex; Movergan; Plurimen
(Foreign brand names outside U.S. in italics)

COST OF THERAPY: $1,378.97 (Parkinsonism; Tablet; 5 mg; 2/day; 365 days)





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