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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (S's) » Sulfamethoxazole and Trimethoprim



DESCRIPTION

Tablets and Suspensions

Sulfamethoxazole; trimethoprim is a synthetic antibacterial combination product available in DS (double strength) tablets, tablets and suspensions for oral administration. Each DS tablet contains 160 mg trimethoprim and 800 mg sulfamethoxazole plus magnesium stearate, pregelatinized starch and sodium starch glycolate. Each tablet contains 80 mg trimethoprim and 400 mg sulfamethoxazole plus magnesium stearate, pregelatinized starch, sodium starch glycolate, FD&C blue no. 1 lake, FD&C yellow no. 6 lake and D&C yellow no. 10 lake. Each teaspoonful (5 ml) of the pediatric suspension or suspension contains 40 mg trimethoprim and 200 mg sulfamethoxazole in a vehicle containing 0.3 percent alcohol, edetate disodium, glycerin, microcrystalline cellulose, parabens (methyl and propyl), polysorbate 80, saccharin sodium, simethicone, sorbitol, sucrose, FD&C yellow no. 6, FD&C red no. 40, flavors and water.

Trimethoprim is 2,4-diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine. It is a white to light yellow, odorless, bitter compound with a molecular weight of 290.32 and a molecular formula of C14H18N4O3.

Sulfamethoxazole is N1-(5-methyl-3-isoxazolyl) sulfanilamide. It is almost white, odorless, tasteless compound with a molecular weight of 253.28 and a molecular formula of C10H11N3O3S.

IV Infusion

Sulfamethoxazole; trimethoprim IV infusion is a sterile solution for intravenous infusion only, and is a synthetic antibacterial combination product. Each ml of Septra IV infusion contains 16 mg trimethoprimn and 80 mg sulfamethoxazole compounded with 40% propylene glycol, 10% ethyl alcohol, and 0.3% diethanolamine; 1% benzyl alcohol and 0.1% sodium metabisulfite added as preservatives, water for injection, and pH adjusted to approximately 10 with sodium hydroxide.

Trimethoprim is 5-[(3,4,5-trimethoxyphenyl)methyl]-2,4-pyrimidinediamin. It is a white to light yellow, odorless, bitter compound with a molecular weight of 290.32 and the molecular formula C14H18N4O3.

CATEGORIES, BRAND NAMES

CATEGORIES: Bronchitis, chronic, acute exacerbation; Diarrhea, travelers'; Infection, ear, middle; Infection, lower respiratory tract; Infection, urinary tract; Pneumonia, pneumocystis; Shigellosis; Pregnancy Category C; FDA Approval Pre 1982; Top 200 Drugs; WHO Formulary

FDA Drug Classes: Sulfonamides Antimicrobials

BRAND NAMES:

BRAND NAMES: Abacin; Abactrim; Acuco; Alcorim-F; Anitrim; Antrimox; Apo-Sulfatrim; Bacdan; Bacidal; Bacin; Bacticel; Bactifor; Bactoprim; Bactramin; Bactrim; Bactrim DS; Bactrim Forte; Bactrimel; Baktar; Bencole; Bethaprim; Biosulten; Briscotrim; BS; Centrim; Chemitrim; Ciplin; Co-Trimoxizole; Colizole; Colizole DS; Comox; Conprim; Cotrim; Cotrim-Diolan; Cotrimel; Deprim; Diseptyl; Dosulfin; Drylin; Duocide; Duratrimet; Ectaprim; Esbesul; Espectrin; Euctrim; Eusaprim; Exbesul; Fectrim; Fermagex; Fortrim; Futin; Gantaprim; Gantrim; Hulin; Ikaprim; Isobac; Isotrim; Kelfiprim; Kepinol; Lagatrim; Lagatrim Forte; Lastrim; Lescot; Medixin; Microtrim; Missile; Nopil; Novotrimel; Omsat; Omstat; Oxaprim; Purbal; Resprim; Resprim Forte; Roubal; Salvatrim; Septra; Septran; Septrin; Septrin DS; Septrin Forte; Septrin S; Setprin; Sigaprim; SMX-TMP; Smz-Tmp; Stopan; Sugaprim; Sulfacet; Sulfamar; Sulfamethoprim; Sulfamethoxazole Trimethoprim; Sulfaprim; Sulfatrim; Sulfinam; Sulfotrimin; Sulfoxaprim; Sulmeprim; Sulthrim; Sultrex; Suprim; Suprin; Tmp Smx; TMS; Triazole; Trim; Trimel; Trimeth/Sulfa; Trimetox; Trimezol; Trimezole; Trimox; Trisul; Trisulcom; Trisulfam; Trisural; Trizole; Ulfaprim; Uro-D S; Urobactrim; Uroplus; Xeroprim; Zamboprim
(Foreign Brand names outside U.S. in italics)

FOREIGN BRAND AVAILABILITY:
Abacin (Italy)
Abactrim (Spain)
Acuco (South-Africa)
Alcorim-F (India)
Anitrim (Mexico)
Antrimox (Ireland)
Apo-Sulfatrim (Canada)
Bacidal (Philippines)
Bacin (Hong-Kong; Malaysia; Thailand)
Bacticel (Argentina)
Bactifor (Spain)
Bactoprim (Indonesia)
Bactramin (Japan)
Bactrim DS (Australia; India)
Bactrim Forte (Austria; Bulgaria; Costa-Rica; Czech-Republic; Dominican-Republic; El-Salvador; Finland; France; Guatemala; Honduras; Nicaragua; Panama; Portugal; Sweden)
Bactrimel (Greece; Netherlands)
Baktar (Japan)
Bencole (South-Africa)
Briscotrim (South-Africa)
BS (Hong-Kong)
Chemitrim (Hong-Kong)
Ciplin (Bahrain; Cyprus; Egypt; Iran; Iraq; Jordan; Kuwait; Lebanon; Libya; Oman; Qatar; Republic-of-Yemen; Saudi-Arabia; Syria; United-Arab-Emirates)
Colizole (India)
Colizole DS (India)
Comox (England)
Conprim (Thailand)
Cotrim-Diolan (Bahrain; Cyprus; Egypt; Iran; Iraq; Jordan; Kuwait; Lebanon; Libya; Oman; Qatar; Republic-of-Yemen; Saudi-Arabia; Syria; United-Arab-Emirates)
Cotrimel (Hong-Kong)
Diseptyl (Israel)
Duocide (Taiwan)
Duratrimet (Germany)
Ectaprim (Mexico)
Esbesul (Slovenia)
Espectrin (Brazil)
Euctrim (Taiwan)
Eusaprim (Austria; Belgium; Finland; France; Germany; Italy; Netherlands; Norway; Sweden; Switzerland)
Fectrim (England)
Fermagex (Philippines)
Gantaprim (Italy)
Gantrim (Italy)
Hulin (Spain)
Ikaprim (Indonesia)
Isobac (Mexico)
Isotrim (Italy)
Kepinol (Germany)
Lagatrim (Bahamas; Bahrain; Barbados; Belize; Benin; Bermuda; Burkina-Faso; Curacao; Cyprus; Egypt; Ethiopia; Gambia; Ghana; Guinea; Guyana; Iran; Iraq; Ivory-Coast; Jamaica; Jordan; Kenya; Kuwait; Lebanon; Liberia; Libya; Malawi; Mali; Mauritania; Mauritius; Morocco; Netherland-Antilles; Niger; Nigeria; Oman; Qatar; Republic-of-Yemen; Saudi-Arabia; Senegal; Seychelles; Sierra-Leone; Sudan; Surinam; Syria; Tanzania; Trinidad; Tunia; Uganda; United-Arab-Emirates; Zambia; Zimbabwe)
Lagatrim Forte (Bahamas; Barbados; Belize; Benin; Bermuda; Burkina-Faso; Curacao; Ethiopia; Gambia; Ghana; Guinea; Guyana; Ivory-Coast; Jamaica; Kenya; Liberia; Malawi; Mali; Mauritania; Mauritius; Morocco; Netherland-Antilles; Niger; Nigeria; Senegal; Seychelles; Sierra-Leone; Sudan; Surinam; Tanzania; Trinidad; Tunia; Uganda; Zambia; Zimbabwe)
Lastrim (Thailand)
Lescot (Argentina)
Medixin (Italy)
Microtrim (Germany)
Missile (Argentina)
Nopil (Bahrain; Cyprus; Ecuador; Egypt; Iran; Iraq; Jordan; Kuwait; Lebanon; Libya; Oman; Qatar; Republic-of-Yemen; Saudi-Arabia; Syria; United-Arab-Emirates)
Novotrimel (Canada)
Omsat (Bahrain; Benin; Burkina-Faso; Cyprus; Egypt; Ethiopia; Gambia; Germany; Ghana; Guinea; Iran; Iraq; Ivory-Coast; Jordan; Kenya; Kuwait; Lebanon; Liberia; Libya; Malawi; Mali; Mauritania; Mauritius; Morocco; Niger; Nigeria; Oman; Qatar; Republic-of-Yemen; Saudi-Arabia; Senegal; Seychelles; Sierra-Leone; Sudan; Syria; Tanzania; Tunia; Uganda; United-Arab-Emirates; Zambia; Zimbabwe)
Oxaprim (Italy; Japan)
Purbal (South-Africa)
Resprim (Australia; Israel)
Resprim Forte (Australia)
Salvatrim (Dominican-Republic; El-Salvador; Honduras; Panama)
Septran (Costa-Rica; Dominican-Republic; El-Salvador; Honduras; India; Panama; South-Africa; Uruguay)
Septrin (Argentina; Australia; Bahrain; Benin; Burkina-Faso; Colombia; Cyprus; Egypt; England; Ethiopia; Gambia; Ghana; Guinea; Hong-Kong; Indonesia; Iran; Iraq; Ivory-Coast; Jordan; Kenya; Korea; Kuwait; Lebanon; Liberia; Libya; Malawi; Malaysia; Mali; Mauritania; Mauritius; Mexico; Morocco; New-Zealand; Niger; Nigeria; Oman; Peru; Philippines; Qatar; Republic-of-Yemen; Saudi-Arabia; Senegal; Seychelles; Sierra-Leone; Spain; Sudan; Syria; Taiwan; Tanzania; Tunia; Uganda; United-Arab-Emirates; Zambia; Zimbabwe)
Septrin DS (Hong-Kong; Thailand)
Septrin Forte (Australia)
Septrin S (Thailand)
Sigaprim (Germany)
Stopan (Japan)
Sugaprim (India)
Sulfacet (Germany)
Sulfinam (Colombia)
Sulfotrimin (Germany)
Sulthrim (Colombia)
Suprim (Peru)
Suprin (Italy)
TMS (Germany)
Trim (Italy; South-Africa)
Trimel (New-Zealand)
Trimetox (Mexico)
Trimezol (Ecuador)
Trimezole (Indonesia)
Trimox (Thailand)
Trisul (New-Zealand)
Trisulcom (Philippines)
Ulfaprim (Indonesia)
Xeroprim (South-Africa)
Zamboprim (Philippines)

COST OF THERAPY: $22.96 (Respiratory Infections; Bactrim Tablet; 400 mg;80 mg; 2/day; 14 days)





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