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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (S's) » Sumatriptan Succinate (subcutaneous)


Sumatriptan succinate injection is a selective 5-hydroxytryptamine1, receptor subtype agonist. Sumatriptan succinate is chemically designated as 3-[2-(dimethylamino)ethyl]-N-methyl-indole-5-methanesulfonamide succinate (1:1).

The empirical formula is C14H21N3O2S·C4H6O4, representing a molecular weight of 413.5.

Sumatriptan succinate is a white to off-white powder that is readily soluble in water and in saline.

Imitrex injection is a clear, colorless to pale yellow, sterile, nonpyrogenic solution for subcutaneous injection. Each 0.5 ml of solution contains 6 mg of sumatriptan (base) as the succinate salt and 3.5 mg of sodium chloride in water for injection. The pH range of the solution is approximately 4.2 to 5.3. The osmolality of the injection is 291 mOsmol.


CATEGORIES: Headache, migraine; Pregnancy Category C; FDA Class 1P ("Priority Review"); Top 200 Drugs; FDA Approved 1992 Dec

FDA Drug Classes: Antimigraine; Pharmaceutical Aids


BRAND NAMES: Imigran; Imigrane; Imiject; Imitrex; Megrelan; Migragesin; Sumitrex
(Foreign Brand names outside U.S. in italics)

Imigrane (France)
Imiject (France)
Megrelan (Colombia)
Migragesin (Colombia)
Sumitrex (India)

HCFA JCODE(S): J3030 6 mg SC

COST OF THERAPY: $98.69 (Migraine; Imitrex Solution; 6 mg/0.5 ml; 1/day; 1 days)

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