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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (S's) » Sumatriptan Succinate


Imitrex is a selective 5-hydroxytryptamine1 receptor subtype agonist. Sumatriptan succinate is chemically designated as 3-[2-(dimethylamino)ethyl]-N-methyl-indole¾5-methanesulfonamide succinate (1:1).

The empirical formula is C14H21N3O2S·C4H6O4, representing a molecular weight of 413.5. Sumatriptan succinate is a white to off-white powder that is readily soluble in water and in saline.

Each Imitrex tablet for oral administration contains 35 or 70 mg of sumatriptan succinate equivalent to 25 or 50 mg of sumatriptan, respectively. Each tablet also contains the inactive ingredients croscarmellose sodium, lactose, magnesium stearate, microcrystalline cellulose, and titanium dioxide dye.


CATEGORIES: Headache, migraine; Pregnancy Category C; FDA Class 1P ("Priority Review"); Top 200 Drugs; FDA Approved 1992 Dec

FDA Drug Classes: Antimigraine; Pharmaceutical Aids


BRAND NAMES: Imigran; Imigrane; Imiject; Imitrex; Megrelan; Migragesin; Sumitrex
(Foreign Brand names outside U.S. in italics)

Imigrane (France)
Imiject (France)
Megrelan (Colombia)
Migragesin (Colombia)
Sumitrex (India)

HCFA JCODE(S): J3030 6 mg SC

COST OF THERAPY: $98.69 (Migraine; Imitrex Solution; 6 mg/0.5 ml; 1/day; 1 days)

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