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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (S's) » Synthetic Estrogens Conjugated



DESCRIPTION

ESTROGENS INCREASE THE RISK OF ENDOMETRIAL CARCINOMA

Close clinical surveillance of all women taking estrogens is important. Adequate diagnostic measures, including endometrial sampling when indicated, should be undertaken to rule out malignancy in all cases of undiagnosed persistent or recurring abnormal vaginal bleeding. There is no evidence that natural estrogens are more or less hazardous than synthetic estrogens at equivalent estrogen doses.


Synthetic conjugated estrogens, A tablets contain a blend of nine (9) synthetic estrogenic substances. The estrogenic substances are sodium estrone sulfate, sodium equilin sulfate, sodium 17a dihydroequilin sulfate, sodium 17a estradiol sulfate, sodium 17b dihydroequilin sulfate, sodium 17a dihydroequilenin sulfate, sodium 17b dihydroequilenin sulfate, sodium equilenin sulfate and sodium 17b estradiol sulfate.

Tablets for oral administration are available in 0.625 mg and 0.9 mg strengths of synthetic conjugated estrogens. Tablets also contain the following inactive ingredients: ethylcellulose, hydroxypropyl methylcellulose, lactose monohydrate, magnesium stearate, polyethylene glycol, polysorbate 80, pregelatinized starch, titanium dioxide, and triethyl citrate.

0.625 mg tablets also contain: FD&C Red No. 40 aluminum lake.

0.9 mg tablets do not contain any color additives.





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