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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (T's) » Terbutaline



DESCRIPTION

Brethine, terbutaline sulfate injection USP, is a b-adrenergic agonist bronchodilator available as a sterile, nonpyrogenic, aqueous solution in ampuls, for subcutaneous administration. Each milliliter of solution contains 1 mg of terbutaline sulfate USP (0.82 mg of the free base); sodium chloride ACS, for isotonicity; and hydrochloric acid ACS, for adjustment to a target pH of 4. Terbutaline sulfate is ()-a-[(tert-butylamino) methyl]-3,5-dihydroxybenzyl alcohol sulfate (2:1) (salt). The empirical formula is (C12H19NO3)2 H2SO4.

Terbutaline sulfate USP is a white to gray-white crystalline powder. It is odorless or has a faint odor of acetic acid. It is soluble in water and in 0.1 N hydrochloric acid, slightly soluble in methanol, and insoluble in chloroform. Its molecular weight is 548.65.





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