(Thiopental Sodium for Injection, USP)
WARNING: MAY BE HABIT FORMING.
Pentothal (Thiopental Sodium for Injection, USP) is a thiobarbiturate,
the sulfur analogue of sodium pentobarbital.
The drug is prepared as a sterile powder and after reconstitution with
an appropriate diluent is administered by the intravenous route.
Pentothal is chemically designated sodium 5-ethyl-5-(1-methylbutyl)-2-thiobarbiturate.
The drug is a yellowish, hygroscopic powder, stabilized with anhydrous
sodium carbonate as a buffer (60 mg/g of thiopental sodium).
Diluents in Pentothal Kits
Ready-To-Mix Syringes and Vials
(For preparing solutions of Thiopental Sodium for Injection, USP)
The following diluents in various container, syringe and vial sizes are
provided in Pentothal Kits, Pentothal Ready-to-Mix Syringes and Vials
for preparing solutions of Pentothal (Thiopental Sodium for Injection,
USP) for clinical use:
Sterile Water for Injection, USP is a sterile, nonpyrogenic preparation
of water for injection which contains no bacteriostat, antimicrobial agents
or added buffers. The pH is 5.7 (5.0 to 7.0).
Sterile Water for Injection, USP is a pharmaceutic aid (solvent) for
intravenous administration only after addition of a solute.
Water is chemically designated H2O.
0.9% Sodium Chloride Injection, USP is a sterile, nonpyrogenic, isotonic
solution of sodium chloride and water for injection. Each mL contains
sodium chloride 9 mg (308 mOsmol/liter calc). It contains no bacteriostat,
antimicrobial agents or added buffers except for pH adjustment. May contain
hydrochloric acid and/or sodium hydroxide for pH adjustment. pH is 5.7
(4.5 to 7.0).
0.9% Sodium Chloride Injection, USP is an isotonic vehicle for intravenous
administration of another solute.
Sodium chloride is chemically designated NaCl, a white crystalline compound
freely soluble in water.
The semi-rigid vial contained in List Nos. 3329, 6418, 6419, 6420 and
6435 is fabricated from a specially formulated polyolefin. It is a copolymer
of ethylene and propylene. The safety of the plastic has been confirmed
by tests in animals according to USP biological standards for plastic
containers. The container requires no vapor barrier to maintain the proper