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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (T's) » Tiagabine


GABITRIL (tiagabine HCl) is an antiepilepsy drug available as 4 mg, 12 mg, 16 mg, and 20 mg tablets for oral administration. Its chemical name is (-)-( R)-1-[4,4-Bis(3-methyl-2-thienyl)-3- butenyl] nipecotic acid hydrochloride, its molecular formula is C20H25NO2S2 HCl, and its molecular weight is 412.0. Tiagabine HCl is a white to off-white, odorless, crystalline powder. It is insoluble in heptane, sparingly soluble in water, and soluble in aqueous base.

Inactive Ingredients: GABITRIL tablets contain the following inactive ingredients: Ascorbic acid, colloidal silicon dioxide, crospovidone, hydrogenated vegetable oil wax, hydroxypropyl cellulose, hydroxypropyl methylcellulose, lactose, magnesium stearate, microcrystalline cellulose, pregelatinized starch, stearic acid, and titanium dioxide.

In addition, individual tablets contain:

  • 4 mg tablets: D&C Yellow No. 10.
  • 12 mg tablets: D&C Yellow No. 10 and FD&C Blue No. 1.
  • 16 mg tablets: FD&C Blue No. 2.
  • 20 mg tablets: D&C Red No. 30.

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