GABITRIL (tiagabine HCl) is an antiepilepsy drug
available as 4 mg, 12 mg, 16 mg, and 20 mg
tablets for oral administration.
Its chemical name is
(-)-( R)-1-[4,4-Bis(3-methyl-2-thienyl)-3- butenyl] nipecotic acid
hydrochloride, its molecular formula
HCl, and its molecular weight
is 412.0. Tiagabine HCl is a white to off-white, odorless, crystalline
powder. It is insoluble
in heptane, sparingly soluble
in water, and soluble
in aqueous base.
Inactive Ingredients: GABITRIL tablets contain the
following inactive ingredients: Ascorbic acid,
colloidal silicon dioxide,
crospovidone, hydrogenated vegetable
oil wax, hydroxypropyl cellulose,
hydroxypropyl methylcellulose, lactose, magnesium
cellulose, pregelatinized starch,
stearic acid, and titanium
In addition, individual tablets contain:
- 4 mg tablets: D&C
Yellow No. 10.
- 12 mg tablets: D&C
Yellow No. 10 and FD&C Blue No. 1.
- 16 mg tablets: FD&C
Blue No. 2.
- 20 mg tablets: D&C
Red No. 30.