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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (T's) » Tizanidine



DESCRIPTION

Zanaflex is a centrally acting alpha2-adrenergic agonist. Tizanidine HCl is a white to off-white fine crystalline powder, odorless or with a faint characteristic odor. Tizanidine is slightly soluble in water and methanol; solubility in water decreases as the pH increases. Its chemical name is 5-chloro-4-(2-imidazolin-2-ylamino)-2, 1,3-benzothiodiazole hydrochloride. Tizanidine's molecular formula is C9H8ClN5S·HCl, its molecular weight is 290.2.

Zanaflex is supplied as 4 mg tablets for oral administration. Zanaflex tablets are composed of the active ingredient tizanidine hydrochloride (4.576 mg equivalent to 4 mg tizanidine base), and the inactive ingredients, silicon dioxide colloidal, stearic acid, microcrystalline cellulose and anhydrous lactose.

CATEGORIES, BRAND NAMES

CATEGORIES: Spasticity; Pregnancy Category C; FDA Approved 1996 Dec; Orphan Drugs

BRAND NAMES: Sirdalud; Sirdalud MR; Sirdalud Retard; Ternelax; Ternelin; Zanaflex
(Foreign brand names outside U.S. in italics)





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