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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (T's) » Trazodone



DESCRIPTION

Trazodone HCl, is an antidepressant chemically unrelated to tricyclic, tetracyclic, or other known antidepressant agents. It is a triazolopyridine derivative designated as 2-[3-{4 -(m- Chlorophenyl)-1-piperazinyl] propyl]s-triazol[4,3-a]-pyridine-3(2H)-one monohydrochloride. Trazodone HCl is a white to off-white crystalline powder which is sparingly soluble in chloroform and water. Its molecular weight is 408.3. The empirical formula is C19H22ClN5O·HCl.

Trazodone HCl is supplied for oral administration in 50 mg, 100 mg, 150 mg, and 300 mg tablets.

Trazodone HCl tablets, 50 mg, contain the following inactive ingredients: dibasic calcium phosphate, castor oil, microcrystalline cellulose, ethylcellulose, FD&C yellow no. 6 (aluminum lake), lactose, magnesium stearate, povidone, sodium starch glycolate, and starch (corn).

Trazodone HCl tablets, 100 mg, contain the following inactive ingredients: dibasic calcium phosphate, castor oil, microcrystalline cellulose, ethylcellulose, lactose, magnesium stearate, povidone, sodium starch glycolate, and starch (corn).

Trazodone HCl tablets, 150 mg, contain the following in active ingredients: microcrystalline cellulose, FD&C yellow no. 6 (aluminum lake), magnesium stearate, pre-gelatinized starch, and stearic acid.

Trazodone HCl tablets, 300 mg, contain the following inactive ingredients: microcrystalline cellulose, yellow ferric oxide, magnesium stearate, sodium starch glycolate, pregelatinized starch, and stearic acid.

CATEGORIES, BRAND NAMES

CATEGORIES: Depression; Pregnancy Category C; FDA Approved 1981 Dec; Top 200 Drugs

FDA Drug Classes: Analgesics, General; Antianxiety; Antiarthritics; Antidepressants

BRAND NAMES:

BRAND NAMES: Beneficat; Bimaran; Deprax; Desirel; Desyrel; Manegan; Molipaxin; Pragmarel; Sideril; Taxagon; Thombran; Trazalon; Trazolan; Trazonil; Trittico

COST OF THERAPY: $548.10 (Depression; Desyrel Tablet; 50 mg; 3/day; 90 days)





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