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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (T's) » Trimethobenzamide



DESCRIPTION

TIGAN brand of
Trimethobenzamide Hydrochloride Capsules/ Suppositories/ Injectable

Chemically, trimethobenzamide HCl is N-[p-[2-(dimethylamino)-ethoxy]benzyl]-3,4,5- trimethoxybenzamide hydrochloride. It has a molecular weight of 424.93.

Capsules

Each 100 mg Tigan capsule for oral use, with opaque blue cap and opaque white body, contains trimethobenzamide hydrochloride equivalent to 100mg.

Each 250 mg Tigan capsule for oral use, with opaque blue cap and body, contains trimethobenzamide hydrochloride equivalent to 250 mg.

Both caps and bodies of the 100 and 250 mg capsules are imprinted with TIGAN® 100 mg and TIGAN® 250 mg, respectively.

Inactive Ingredients: FD&C Blue No. 1, FD&C Red No. 3, lactose, magnesium stearate, starch and titanium dioxide.

Suppositories

Suppositories (200 mg): Each suppository contains 200 mg trimethobenzamide hydrochloride and 2% benzocaine in a base compounded with polysorbate 80, white beeswax and propylene glycol monostearate.

Suppositories, Pediatric (100 mg): Each suppository contains 100 mg trimethobenzamide hydrochloride and 2% benzocaine in a base compounded with polysorbate 80, white beeswax and propylene glycol monostearate.

Injectable

Ampuls: Each 2 mL ampul contains 200 mg trimethobenzamide hydrochloride compounded with 0.2% parabens (methyl and propyl) as preservatives, 1 mg sodium citrate and 0.4 mg citric acid as buffers and pH adjusted to approximately 5.0 with sodium hydroxide.

Multi-Dose Vials: Each mL contains 100 mg trimethobenzamide hydrochloride compounded with 0.45% phenol as preservative, 0.5 mg sodium citrate and 0.2 mg citric acid as buffers and pH adjusted to approximately 5.0 with sodium hydroxide.

Thera-Ject® (Disposable Syringes): Each 2 mL contains 200 mg trimethobenzamide hydrochloride compounded with 0.45% phenol as preservative, 1 mg sodium citrate and 0.4 mg citric acid as buffers, 0.2 mg disodium edetate as stabilizer and pH adjusted to approximately 5.0 with sodium hydroxide.





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