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Cordarone is a member of a
new class of antiarrhythmic
drugs with predominantly Class III (Vaughan Williams classification)
effects, available for oral administration as pink, scored tablets containing
200 mg of amiodarone hydrochloride.
The inactive ingredients present
are colloidal silicon dioxide,
lactose, magnesium stearate,
povidone, starch, and FD&C
Red 40. Cordarone is a benzofuran derivative: 2-butyl-3-benzofuranyl 4-[2-(diethylamino)-ethoxyl-3,5diiodophenyl
ketone hydrochloride. It is not chemically related to any other available
Amiodarone HCl is a white
to cream-colored crystalline
powder. It is slightly soluble
in water, soluble in alcohol,
and freely soluble in chloroform.
It contains 37.3% iodine by