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You are here: Home » Products Listed by Brand » McKesson Products » Drug Reference (A's) » Astemizole


Hismanal (astemizole) is a histamine H1-receptor antagonist available in scored white tablets for oral use. Each tablet contains 10 mg of astemizole, and as inactive ingredients: lactose, cornstarch, microcrystalline cellulose, pregelatinized starch, povidone K90, magnesium stearate, colloidal silicon dioxide, and sodium lauryl sulfate. Astemizole is chemically designated as 1-[(4-fluorophenyl) -methyl] -N-[1-[2-(4-methoxyphenyl) ethyl]-4 -piperidinyl]-1H-benzimidazol-2-amine, with a molecular weight of 458.58. The empirical formula is C28H31FN4O.

Astemizole is a white to slightly off-white powder; it is insoluble in water, slightly soluble in ethanol and soluble in chloroform and methanol.


CATEGORIES: Asthma, bronchial (treatment adjunct); Pruritus, associated with pityriasis rosea (treatment)

FDA Drug Class: Antihistamines

BRAND NAMES: Adistan; Alestol; Anminlin; Asemin; Astelong; Astem; Astemina; Astemizol; Astin; Astimal; Astizol; Cilergil; Eumine; Hismanal; Hisnot; Hispral; Histalong; Histamen; Histaminos; Histamizol; Histazole; Irene; Metodik; Mildugen; Pollon; Pollon-Eze; Retolen; Scantihis; Simprox; Sines; Sisnal; Stemiz; Tenon
(Foreign brand names outside U.S. in italics)

COST OF THERAPY: $62.24 (Rhinitis; Tablet; 10 mg; 1/day; 30 days)

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