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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (B's) » Baclofen


Baclofen is a muscle relaxant and antispastic. Its chemical name is 4- amino-3- (4-chlorophenyl)- butanoic acid.

Baclofen is a white to off-white, odorless or practically odorless crystalline powder, with a molecular weight of 213.66. It is slightly soluble in water, very slightly soluble in methanol, and insoluble in chloroform.

Baclofen tablets are available as 10-mg and 20-mg tablets for oral administration.

Inactive Ingredients

Baclofen tablets: Cellulose compounds, magnesium stearate, povidone, and starch.

Baclofen injection: is a sterile, pyrogen-free, isotonic solution free of antioxidants, preservatives or other potentially neurotoxic additives indicated only for intrathecal administration. The drug is stable in solution at 37° C and compatible with CSF. Each milliliter of baclofen injection contains baclofen U.S.P. 500 mcg or 2000 mcg and sodium chloride 9 mg in Water for Injection; pH range is 5-7. Each ampule is intended for SINGLE USE ONLY. Discard any unused portion. DO NOT AUTOCLAVE.


CATEGORIES: Multiple Sclerosis; Spasticity; Spinal Cord Injury; FDA Approval Pre 1982; Pregnancy Category C; Orphan Drugs

FDA Drug Class: Diagnostics - Radiopharmaceuticals; Skeletal Muscle Hyperactivity

BRAND NAMES: Alpha-Baclofen; Baclon; Baclosal; Baclospas; Baklofen; Clofen; Lebic; Lioresal; Mulax; Pacifen; Spinax
(Foreign brand names outside U.S. in italics)

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