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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (C's) » Calcitonin (salmon)



DESCRIPTION

Calcitonin is a polypeptide hormone secreted by the parafollicular cells of the thyroid gland in mammals and by the ultimobranchial gland of birds and fish.

Calcitonin (salmon) is a synthetic polypeptide of 32 amino acids in the same linear sequence that is found in calcitonin of salmon origin.

Injection: It is provided in sterile solution for subcutaneous or intramuscular injection. Each milliliter contains 200 IU (MRC) of calcitonin (salmon), 5 mg phenol (as preservative), with sodium chloride, sodium acetate, acetic acid, and sodium hydroxide to adjust tonicity and pH.

Nasal Spray: It is provided in 2 ml fill glass bottles as a solution for nasal administration. This is sufficient medication for 14 doses. Each milliliter contains calcitonin (salmon) 2200 IU (corresponding to 200 IU per 0.09 ml actuation), sodium chloride 8.5 mg, benzalkonium chloride 0.10 mg, nitrogen, hydrochloric acid (added as necessary to adjust pH) and purified water.

The activity of calcitonin (salmon) nasal spray is stated in International Units based on bioassay in comparison with the International Reference Preparation of calcitonin (salmon) for Bioassay, distributed by the National Institute of Biologic Standards and Control, Holly Hill, London.

CATEGORIES, BRAND NAMES

CATEGORIES: Hypercalcemia; Osteoporosis, postmenopausal; Paget's disease; Pregnancy Category C; FDA Approval Pre 1982; Top 200 Drugs; Orphan Drugs

FDA Drug Classes: Calcium Metabolism

BRAND NAMES:

BRAND NAMES: Biocalcin; Boncalmon; Cadens; Calcimar; Calcinin; Calco; Calsynar; Caltine; Miacalcic; Miacalcin; Oseum; Osteocalcin; Rocalcit; Tonocalcin; Zycalcit
(Foreign Brand names outside U.S. in italics)

FOREIGN BRAND AVAILABILITY:
Biocalcin (Korea)
Boncalmon (Korea)
Cadens (France)
Calcinin (Taiwan)
Calco (Thailand)
Calsynar (Australia; Benin; Burkina-Faso; Ethiopia; Gambia; Ghana; Guinea; Hong-Kong; Ivory-Coast; Kenya; Liberia; Malawi; Mali; Mauritania; Mauritius; Morocco; Niger; Nigeria; Senegal; Seychelles; Sierra-Leone; Sudan; Tanzania; Tunia; Uganda; Zambia; Zimbabwe)
Caltine (Canada)
Miacalcic (Hong-Kong; Mexico; New-Zealand)
Oseum (Mexico)
Rocalcit (Colombia)
Tonocalcin (Indonesia)
Zycalcit (India)

COST OF THERAPY: $4872.75 (Osteoporosis; Calcimar Solution; 200 iu/ml; 0.5 ml/day; 365 days)

HCFA JCODE(S): J0630 up to 400 units SC, IM





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