DESCRIPTION

Cetirizine HCl is an orally active and selective H₁-receptor antagonist. The chemical name is (±) - [2- [4- [ (4-chlorophenyl)phenylmethyl] -1- piperazinyl] ethoxy]acetic acid, dihydrochloride. Cetirizine HCl is a racemic compound with an empirical formula of C₂₁H₂₅C1N₂O₃·2HCl. The molecular weight is 461.82.

Cetirizine HCl is a white, crystalline powder and is water soluble. Zyrtec tablets are formulated as white, film-coated, rounded-off rectangular shaped tablets for oral administration and are available in 5 and 10 mg strengths. Inactive Ingredients: Lactose; magnesium stearate; povidone; titanium dioxide; hydroxypropyl methylcellulose; polyethylene glycol; and corn starch.

Zyrtec syrup is a colorless to slightly yellow syrup containing cetirizine HCl at a concentration of 1 mg/ml (5 mg/5 ml) for oral administration. The pH is between 4 and 5. Inactive Ingredients: Banana flavor; glacial acetic acid; glycerin; grape flavor; methylparaben; propylene glycol; propylparaben; sodium acetate; sugar syrup; and water.

CATEGORIES, BRAND NAMES

CATEGORIES: Rhinitis, perennial allergic; Rhinitis, seasonal allergic; Urticaria, chronic; FDA Approved 1995 Dec; Top 200 Drugs; Pregnancy Category B

FDA Drug Classes: Antihistamines

BRAND NAMES:

BRAND NAMES: Alercet; Alergex; Alerid; Certex-24; Cetrine; Cetzine; Cezin; Histazine; Riztec; Ryzen; Triz; Virlix; Xero-sed; Zirtin; Zyrtec; Zyrzine
(Foreign Brand names outside U.S. in italics)

FOREIGN BRAND AVAILABILITY:
Alercet (Colombia)
Alergex (Colombia)
Alerid (Bahrain; Cyprus; Egypt; Iran; Iraq; Jordan; Kuwait; Lebanon; Libya; Oman; Qatar; Republic-Of-Yemen; Saudi-Arabia; Syria; United-Arab-Emirates)
Cetrine (Colombia)
Cetzine (India)
Cezin (India)
Histazine (Israel)
Riztec (Indonesia)
Ryzen (Indonesia)
Triz (India)
Virlix (Italy; Mexico; Philippines; Portugal; Spain)
Xero-sed (India)
Zirtin (India)
Zyrzine (Thailand)

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