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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (C's) » Chlorothiazide


Chlorothiazide is a diuretic and antihypertensive. It is 6-chloro-2H-1,2,4-benzothia-diazine-7sulfonamide 1, 1-dioxide. Its molecular formula is C7H6CIN304S2.

It is a white, or practically white crystalline compound with a molecular weight of 295.72 which is very slightly soluble in water, but readily soluble in dilute aqueous sodium hydroxide. It is soluble in urine to the extent of about 150 mg per 100 mL at pH 7.

Each tablet for oral administration contains either 250 mg or 500 mg of chlorothiazide and the following inactive ingredients: colloidal silicon dioxide, croscarmellose sodium-Type A, magnesium stearate, microcrystalline cellulose, sodium lauryl sulfate.

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