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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (C's) » Cosyntropin



DESCRIPTION

FOR DIAGNOSTIC USE ONLY
CORTROSYN® (cosyntropin) for injection

Cortrosyn® (cosyntropin) for injection is a sterile lyophilized powder in vials containing 0.25mg of Cortrosyn® and 10mg of mannitol to be reconstituted with lmL sodium chloride for injection, USP as solvent. Administration is by intravenous or intramuscular injection. Cosyntropin is 1-24 corticotropin, a synthetic subunit of ACTH. It is an open chain polypeptide containing, from the N terminus, the first 24 of the 39 amino acids of natural ACTH. The sequence of amino acids in the 1-24 compound is as follows:

Set
1

Tyr
2

Ser
3

Met
4

Glu
5

His
6

Phe
7

Arg
8

Trp
9

Gly
10

Lys
11

Pro
12

Val
13

Gly
14

Lys
15

Lys
16

Arg
17

Arg
18

Pro
19

Val
20

Lys
21

Val
22

Tyr
23

Pro
24





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