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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (E's) » Edetate



The use of this drug in any particular patient is recommended only when the severity of the clinical condition justifies the aggressive measures associated with this type of therapy.

Edetate Disodium Injection, USP is a sterile, nonpyrogenic, concentrated solution of edetate disodium in water for injection which, as a result of a pH adjustment with sodium hydroxide, contains varying amounts of disodium and trisodium salts. After dilution, it is administered by intravenous infusion.

Each mL contains: Edetate Disodium anhydrous 150 mg, in Water for Injection q.s. pH is adjusted with Sodium Hydroxide and if necessary Hydrochloric Acid. Approximate pH is 7 (range 6.5 - 7.5).

Edetate disodium is classified as a clinical chelating agent for emergency lowering of serum calcium in hypercalcemia.

The solution contains no bacteriostat, antimicrobial agent or buffer (except for pH adjustment) and is intended only for use (after dilution) as a single dose infusion. When smaller doses are required, the unused portion should be discarded.

Edetate Disodium, USP is chemically designated disodium (ethylenedinitrilo) tetraacetate dihydrate, a white crystalline powder soluble in water. It is also described as the disodium salt of ethylenediaminetetraacetic acid (EDTA)

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