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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (G's) » Guaifenesin (oral)



DESCRIPTION

Guaifenesin (glyceryl guaiacolate) has the chemical name 3-(2- methoxyphenoxy)-1,2-propanediol. Its molecular formula is C10H14O4 with a molecular weight of 198.21. It is a white or slightly gray crystalline substance with a slightly bitter aromatic taste. One gram dissolves in 20 mL water at 25° C; it is freely soluble in ethanol. Guaifenesin is readily absorbed from the GI tract and is rapidly metabolized and excreted in the urine. Guaifenesin has a plasma half- life of one hour. The major urinary metabolite is b-(2-methoxyphenoxy) lactic acid.

ORGANIDIN® NR* (* Newly Reformulated) (guaifenesin) is an expectorant available for oral administration as:

Tablets: each containing 200 mg guaifenesin, USP.

Other ingredients: Corn starch, croscarmellose sodium, FD&C Red No. 40, magnesium stearate, microcrystalline cellulose.

Liquid: each teaspoonful (5 mL) containing 100 mg guaifenesin, USP.

Other ingredients: Caramel, citric acid, flavor (raspberry), glycerin, propylene glycol, purified water, saccharin sodium, sodium benzoate, sorbitol solution.

TUSSI-ORGANIDIN® NR* (* Newly Reformulated) and TUSSI-ORGANIDIN® DM NR* (* Newly Reformulated) are antitussive-expectorant combinations available for oral administration as liquids.

TUSSI-ORGANIDIN® NR* (* Newly Reformulated) is a clear red liquid with a raspberry flavor. Each teaspoonful (5 mL) contains guaifenesin, USP 100 mg and codeine phosphate, USP 10 mg. (Warning: May be habit- forming)

Other ingredients: Citric acid, FD&C Red No.40, flavor (artificial), glycerin, propylene glycol, purified water, saccharin sodium, sodium benzoate, sorbitol.

TUSSI-ORGANIDIN® DM NR* (* Newly Reformulated) Liquid is a clear yellow liquid with a raspberry flavor. Each teaspoonful (5 mL) contains guaifenesin, USP 100 mg and dextromethorphan hydrobromide, USP 10 mg.

Other ingredients: Citric acid, D& C Yellow No.10, FD&C Red No.40, flavor (artificial), glycerin, propylene glycol, purified water, saccharin sodium, sodium benzoate, sorbitol.





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