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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (H's) » Hydrochlorothiazide


Hydrochlorothiazide is a diuretic and antihypertensive. It is the 3,4-dihydro derivative of chlorothiazide. Its chemical name is 6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide. Its empirical formula is C7H8ClN3O4S2.

It is a white, or practically white, crystalline powder with a molecular weight of 297.72, which is slightly soluble in water, but freely soluble in sodium hydroxide solution.

Hydrochlorothiazide is supplied as 25 mg, 50 mg and 100 mg tablets for oral use.

Each tablet contains the following inactive ingredients: calcium phosphate, FD&C Yellow 6, gelatin, lactose, magnesium stearate, starch and talc.


CATEGORIES: Edema, secondary to corticosteroid therapy; Edema, secondary to estrogen therapy; Edema, secondary to glomerulonephritis; Edema, secondary to heart failure; Edema, secondary to hepatic cirrhosis; Edema, secondary to nephrotic syndrome; Edema, secondary to renal dysfunction; Edema, secondary to renal failure; Hypertension, essentia; Pregnancy Category B; WHO Formulary; Top 200 Drugs

FDA Drug Class: Antihypertensives; Diuretics

BRAND NAMES: Apo-Hydro; Aquazide H; Carozide; Clothia; Dichlothiazide; Dichlotride; Dichlozid; Diclotride; Didralin; Disothiazide; Diuret-P; Diurex; Diurizid; Esidrex; Esidrix; H.C.T.; Hidrenox; Hidrosaluretil; Hydrex; Hydrex-semi; Hydro Par; Hydro-T; Hydrochlorzide; Hydrocot; Hydrodiuril; Hydrosaluric; Hydrozide; Idrodiuvis; Manschitt; Maschitt; Microzide; Natrimax; Nefrol; Neoflumen; Newtolide; Oretic; Pantemon; Servithiazid; Tandiur; Urirex; Zide
(Foreign brand names outside U.S. in italics)

Apo-Hydro (Canada; Malaysia)
Clothia (Japan)
Dichlothiazide (Russia)
Dichlotride (Australia; Belgium; Denmark; Hong-Kong; Japan; Netherlands; New-Zealand; Norway; Philippines; South-Africa; Sweden; Taiwan; Thailand)
Dichlozid (Korea)
Diclotride (Colombia; Mexico)
Didralin (Malaysia; Thailand)
Disothiazide (Israel)
Diuret-P (Thailand)
Diurex (Argentina)
Diurizid (Colombia)
Esidrex (Austria; Bahamas; Bahrain; Barbados; Belize; Benin; Bermuda; Burkina-Faso; Curacao; Cyprus; Egypt; Ethiopia; France; Gambia; Ghana; Guinea; Guyana; India; Iran; Iraq; Israel; Italy; Ivory-Coast; Jamaica; Japan; Jordan; Kenya; Kuwait; Lebanon; Liberia; Libya; Malawi; Mali; Mauritania; Mauritius; Morocco; Netherland-Antilles; Netherlands; Niger; Nigeria; Norway; Oman; Puerto-Rico; Qatar; Republic-of-Yemen; Saudi-Arabia; Senegal; Seychelles; Sierra-Leone; South-Africa; Spain; Sudan; Surinam; Sweden; Switzerland; Syria; Tanzania; Trinidad; Tunia; Uganda; United-Arab-Emirates; Zambia; Zimbabwe)
H.C.T. (Indonesia)
Hidrenox (Argentina)
Hidrosaluretil (Spain)
Hydrex (Finland)
Hydrex-semi (Finland)
Hydrochlorzide (Malaysia)
Hydrosaluric (England)
Hydrozide (Hong-Kong; Thailand)
Maschitt (Japan)
Newtolide (Japan)
Pantemon (Japan)
Servithiazid (Thailand)
Tandiur (Argentina)

COST OF THERAPY: $91.25 (Hypertension; Esidrix Tablet; 50 mg; 1/day; 365 days)

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