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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (H's) » Hydrocortisone and Pramoxine



DESCRIPTION

ProctoFoam HC (hydrocortisone acetate 1% and pramoxine hydrochloride 1%) is a topical aerosol foam for anal use containing hydrocortisone acetate 1% and pramoxine hydrochloride 1% in a hydrophilic base containing cetyl alcohol, emulsifying wax, methylparaben, polyoxyetlheylene-10 stearyl ether, propylene, glycol, propylparaben, purified water, trolamine, and inert propellants: isobutane and propane.

PROCTOFOAM®-HC contains a synthetic corticosteroid used as an anti-inflammatory/antipruritic agent and a local anesthetic.

Hydrocortisone Acetate

Molecular weight: 404.51,
Solubility of hydrocortisone acetate in water: 1 mg/100 mL.
Chemical name: Pregn-4-ene-3,20-dione,21-(acetyloxy) -11,17-dihydroxy-, (11b)-.

Pramoxine Hydrochloride

Molecular weight: 329.87.
Pramoxine hydrochloride is freely soluble in water.
Chemical name: Morpholine 4-[3-(4-butoxyphenoxy)propyl]-,hydrochloride.




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