The topical corticosteroids constitute a class of primarily synthetic
steroids used as anti-inflammatory and anti-pruritic agents. Hydrocortisone
is included in this class of synthetic corticosteroid.
Chemically, hydrocortisone is pregna-4-ene3,20-dione,11,17,21-trihydroxy-(11B);
its molecular formula is C21H30O5 ; its
molecular weight is 362.47; its Chemical Abstract Service (CAS) registry
number is 50-23-7
Each gram of Hydrocortisone Cream USP 1 % provides 10 mg of hydrocortisone
in a nonstaining water washable cream base consisting of stearyl alcohol,
glyceryl monostearate, polyoxyl 40 stearate, isopropyl palmitate, paraffin,
sorbitan monostearate, glycerin, lactic acid, potassium sorbate and purified
Each gram of Hydrocortisone Ointment USP 1% provides 10 mg of hydrocortisone
in a white petrolatum base.