Pandel (hydrocortisone probutate cream) Cream, 0.1%
Pandel Cream contains hydrocortisone probutate, a synthetic adrenocorticosteroid,
for dermatological use. The topical corticosteroids constitute a class
of primarily synthetic steroids used as anti-inflammatory and anti-pruritic
agents. Hydrocortisone probutate is a tasteless and odorless white crystalline
powder practically insoluble in hexane or water, slightly soluble in ether,
and very soluble in dichloromethane, methanol and acetone. Chemically,
it is 11b,17,21-trihydroxypregn-4-ene-3, 20-dione
17-butyrate 21-propionate. It has the following molecular formula C28H40O7 with
a molecular weight of 488.62.
Each gram of Pandel (hydrocortisone probutate cream) Cream, 0.1% contains:
1 mg of hydrocortisone probutate in a cream base of propylene glycol,
white petrolatum, light mineral oil, stearyl alcohol, polysorbate 60,
sorbitan monostearate, glyceryl monostearate, PEG-20 stearate, glyceryl
stearate SE, methylparaben, butylparaben, citric acid anhydrous, sodium
citrate anhydrous, and purified water.