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You are here: Home » Products Listed by Brand » McKesson Products » Drug Reference (A's) » Acyclovir (Injectable)



DESCRIPTION

IV Infusion

Zovirax is the brand name for acyclovir, an antiviral drug active against herpesviruses. Zovirax Sterile Powder is a formulation for intravenous administration. Each 5.49 mg of sterile lyophilized acyclovir sodium is equivalent to 5 mg acyclovir.

The chemical name of acyclovir sodium is 9-[(2-hydroxyethoxy)methyl] guanine sodium.

Acyclovir sodium is a white, crystalline powder with a molecular weight of 247 daltons, and a solubility in water exceeding 100 mg/ml. Each 500 mg or 1000 mg vial of acyclovir sterile powder when reconstituted with 10 ml or 20 ml, respectively, sterile diluent yields 50 mg/ml acyclovir (pH approximately 11). Further dilution in any appropriate intravenous solution must be performed before infusion (see Method of Preparation ). At physiologic pH, acyclovir exists as the un-ionized form with a molecular weight of 225 daltons and a maximum solubility of 2.5 mg/ml at 37C.

CATEGORIES, BRAND NAMES

CATEGORIES: Chickenpox; Herpes Simplex; Herpes; Herpes Genitalis; Herpes Simplex; Herpes Simplex Encephalitis; Herpes Zoster; Sexually Transmitted Diseases; Varicella; Varicella Zoster; Pregnancy Category C; Pregnancy Category B; FDA Approved 1982 Mar; Patent Expiration 1997 Apr; Top 200 Drugs FDA Drug Class: Antifungals; Antivirals; Dermatologics

BRAND NAMES: Acic Creme; Acicloftal; Aciclor; Aciclosina; Aclovir; Acyclo-V; Acyvir; Azovir; Cicloferon; Cicloviral; Clinovir; Clovix; Cusiviral; Cyclivex; Cyclovir; Deherp; Eduvir; Herpefug; Herpex; Herpoviric Rp Creme; Hexidol; Inmerax; Lisovyr; Maynor; Norum; Oppvir; Poviral; Quavir; Supraviran Creme; Vacrovir; Vicorax; Virogon; Virex; Virless; Zevin; Zoter; Zovir; Zovirax; Zyclir

COST OF THERAPY: $128.32 (Herpes Zoster; Tablet; 800 mg; 5/day; 7 days)





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