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You are here: Home » Products Listed by Brand » McKesson Products » Drug Reference (A's) » Amlodipine



DESCRIPTION

Amlodipine besylate is a long-acting calcium channel blocker.

Amlodipine besylate is chemically described as (R.S.) 3-ethyl-5-methyl-2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate benzenesulphonate. Its empirical formula is: C20H25ClN2O5·C6H6O3S.

Amlodipine besylate is a white crystalline powder with a molecular weight of 567.1. It is slightly soluble in water and sparingly soluble in ethanol. Amlodipine besylate tablets are formulated as white tablets equivalent to 2.5, 5 and 10 mg of amlodipine for oral administration. In addition to the active ingredient, amlodipine besylate, each tablet contains the following inactive ingredients: microcrystalline cellulose, dibasic calcium phosphate anhydrous, sodium starch glycolate, and magnesium stearate.

CATEGORIES, BRAND NAMES

CATEGORIES: Angina, chronic stable; Angina, variant; Hypertension, essential; Pregnancy Category C; FDA Class 1S ("Standard Review"); FDA Approved 1992 Jul; Top 200 Drugs

FDA Drug Classes: Antihypertensives; Calcium Channel Blockers

BRAND NAMES:

BRAND NAMES: Amcard; Amdepin; Amdipin; Amlodin; Amlopin; Amlor; Amlosyn; Calchek; Istin; Norvas; Norvasc; Norvask; Tensivask
(Foreign Brand names outside U.S. in italics)

FOREIGN BRAND AVAILABILITY:
Amcard (India)
Amdepin (Benin; Burkina-Faso; Ethiopia; Gambia; Ghana; Guinea; Ivory-Coast; Kenya; Liberia; Malawi; Mali; Mauritania; Mauritius; Morocco; Niger; Nigeria; Senegal; Seychelles; Sierra-Leone; South-Africa; Sudan; Tanzania; Tunia; Uganda; Zambia; Zimbabwe)
Amdipin (Colombia)
Amlodin (Japan)
Amlopin (India)
Amlor (Belgium; France)
Amlosyn (Colombia)
Istin (England; Ireland)
Norvas (Colombia; Mexico; Spain)
Norvask (Bulgaria; Indonesia)
Tensivask (Indonesia)

COST OF THERAPY: $500.05 (Hypertension; Norvasc Tablet; 5 mg; 1/day; 365 days)





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