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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (C's) » Cefprozil


Cefprozil is a semi-synthetic broad-spectrum cephalosporin antibiotic.

Cefprozil is a cis and trans isomeric mixture (³ 90% cis). The chemical name for the monohydrate is (6R,7R)-7-((R)-2-amino-2-(p-hydroxy-phenyl)acetamido)-8-oxo-3-propenyl-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid monohydrate.

Cefprozil is a white to yellowish powder with a molecular formula for the monohydrate of C18H19N3O5S·H2O and a molecular weight of 407.45.

Cefzil tablets contain cefprozil equivalent to 250 mg or 500 mg of anhydrous cefprozil. In addition, each tablet contains the following inactive ingredients: cellulose, hydroxypropylmethylcellulose, magnesium stearate, methylcellulose, simethicone, sodium starch glycolate, polyethylene glycol, polysorbate 80, sorbic acid and titanium dioxide. The 250 mg tablets also contain FD&C yellow No. 6.

Cefzil for oral suspension contains cefprozil equivalent to 125 mg or 250 mg anhydrous cefprozil per 5 ml constituted suspension. In addition, the oral suspension contains the following inactive ingredients: aspartame, cellulose, citric acid, colloidal silicone dioxide, FD&C red No. 3, flavors (natural and artificial), glycine, polysorbate 80, simethicone, sodium benzoate, sodium carboxymethylcellulose, sodium chloride, and sucrose.


CATEGORIES: Bronchitis, acute; Bronchitis, chronic, acute exacerbation; Infection, lower respiratory tract; Infection, skin and skin structures; Infection, upper respiratory tract; Pharyngitis; Tonsillitis; FDA Class 1C ("Little or No Therapeutic Advantage"); FDA Approved 1991 Dec; Pregnancy Category B; Top 200 Drugs

FDA Drug Classes: Cephalosporins


BRAND NAMES: Cefzil; Procef; Prozef
(Foreign Brand names outside U.S. in italics)

Prozef (South-Africa)

COST OF THERAPY: $183.12 (Respiratory Infections; Cefzil Tablet; 500 mg; 2/day; 14 days)

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