About UsContact UsFAQsView Our NewsletterHiringTrack OrderView Cart MY ACCOUNT Ph no: (609) 848-8890
Shop with Confidence
Yahoo Shopping 5 Star- Top service Site
Email this page to your friends
Subscribe to our Newsletter!

Translate This Page:

Mastercard Visa Discover JCB

Go Daddy $1.99 Domains
You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (D's) » Digoxin


Digoxin is one of the cardiac (or digitalis) glycosides, a closely related group of drugs having in common specific effects on the myocardium. These drugs are found in a number of plants. Digoxin is extracted from the leaves of Digitalis lanata. The term "digitalis" is used to designate the whole group of glycosides. The glycosides are composed of two portions: a sugar and a cardenolide (hence "glycosides").

Digoxin is described chemically as (3b, 5b, 12b)-3-[(O-2,6-dideoxy-b-D-ribo-hexopyranosyl-(14)-O-2,6-dideoxy-b-D-ribo-hexopyranosyl-(14)-2,6-dideoxy-b-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxy-card-20(22)-enolide. Its molecular formula is C41H64O14, and its molecular weight is 780.95.

Digoxin exists as odorless white crystals that melt with decomposition above 230°C. The drug is practically insoluble in water and in ether; slightly soluble in diluted (50%) alcohol and in chloroform; and freely soluble in pyridine.

Tablets: Lanoxin is supplied as 125-mcg (0.125-mg) or 250-mcg (0.25-mg) tablets for oral administration. Each tablet contains the labeled amount of digoxin and the following inactive ingredients: corn and potato starches, lactose, and magnesium stearate. In addition, the dyes used in the 125-mcg (0.125-mg) tablets are D&C yellow no. 10 and FD&C yellow no. 6.

Capsules: Lanoxicaps is a stable solution of digoxin enclosed within a soft gelatin capsule for oral use. Each capsule contains the labeled amount of digoxin dissolved in a solvent comprised of polyethylene glycol 400, 8% ethyl alcohol, propylene glycol, and purified water. Inactive ingredients in the Lanoxin capsule shell include FD&C red no. 40 (0.05-mg capsule), D&C yellow no. 10 (0.1-mg and 0.2-mg capsules), FD&C blue no. 1 (0.2 mg capsule), gelatin, glycerin, methylparaben and propylparaben (added as preservatives), purified water and sorbitol. Capsules are printed with edible ink.

Pediatric Elixir: Lanoxin elixir pediatric is a stable solution of digoxin specially formulated for oral use in infants and children. Each ml contains 50 mg (0.05 mg) digoxin. The lime-flavored elixir contains the inactive ingredients alcohol 10%, methylparaben 0.1% (added as a preservative), citric acid, D&C green no. 5 and yellow no. 10, flavor, propylene glycol, sodium phosphate, and sucrose. Each package is supplied with a specially calibrated dropper to facilitate the administration of accurate dosage even in premature infants. Starting at 0.2 ml, this 1-ml dropper is marked in divisions of 0.1 ml, each corresponding to 5 mg (0.005 mg) digoxin.

Lanoxin Injection (Including Pediatric): Lanoxin injection is a sterile solution of digoxin for intravenous injection. The vehicle contains 40% propylene glycol and 10% alcohol. The injection is buffered to a pH of 6.8 to 7.2 with 0.17% sodium phosphate and 0.08% anhydrous citric acid. For Adult Injection: Each 2-ml ampul contains 500 mg (0.5 mg) digoxin (250 mg [0.25 mg] per ml). For Pediatric Injection: Each 1-ml ampul contains 100 mg (0.1 mg) digoxin. Dilution is not required.


CATEGORIES: Fibrillation, atrial; Heart failure, congestive; Pregnancy Category C; FDA Approved 1954 Nov; Top 200 Drugs; WHO Formulary

FDA Drug Classes: Antiarrhythmics; Cardiac Glycosides


BRAND NAMES: Cardigox; Cardiogoxin; Cardioxin; Cardoxin; Coragoxine; Digacin; Digicor; Digomal; Digon; Digosin; Digoxine Navtivelle; Digoxina-Sandoz; Digoxin-Sandoz; Digoxin-Zori; Dilanacin; Eudigox; Fargoxin; Grexin; Lanacordin; Lanacrist; Lanicor; Lanikor; Lanorale; Lanoxicaps; Lanoxin; Lanoxin PG; Lenoxicaps; Lenoxin; Lifusin; Mapluxin; Natigoxin; Novodigal; Purgoxin; Toloxin
(Foreign Brand names outside U.S. in italics)

Cardigox (Belgium)
Cardiogoxin (Argentina)
Cardioxin (India)
Digacin (Germany)
Digicor (Colombia)
Digomal (Italy)
Digosin (Japan; Korea)
Digoxine Navtivelle (France)
Digoxina-Sandoz (Peru)
Digoxin-Sandoz (Benin; Burkina-Faso; Ethiopia; Gambia; Ghana; Guinea; Indonesia; Ivory-Coast; Japan; Kenya; Liberia; Malawi; Mali; Mauritania; Mauritius; Morocco; Niger; Nigeria; Senegal; Seychelles; Sierra-Leone; South-Africa; Sudan; Tanzania; Tunia; Uganda; Zambia; Zimbabwe)
Digoxin-Zori (Israel)
Dilanacin (Cyprus; Egypt; Iraq; Jordan; Sudan)
Eudigox (Italy)
Fargoxin (Indonesia)
Grexin (Thailand)
Lanacordin (Spain)
Lanacrist (Sweden)
Lanicor (Argentina; Austria; Bahamas; Bahrain; Barbados; Belize; Benin; Bermuda; Burkina-Faso; Costa-Rica; Curacao; Cyprus; Czech-Republic; Dominican-Republic; Ecuador; Egypt; El-Salvador; Ethiopia; Gambia; Germany; Ghana; Greece; Guatemala; Guinea; Guyana; Honduras; Iran; Iraq; Israel; Italy; Ivory-Coast; Jamaica; Jordan; Kenya; Kuwait; Lebanon; Liberia; Libya; Malawi; Mali; Mauritania; Mauritius; Morocco; Netherland-Antilles; Niger; Nigeria; Oman; Panama; Portugal; Puerto-Rico; Qatar; Republic-Of-Yemen; Saudi-Arabia; Senegal; Seychelles; Sierra-Leone; South-Africa; Sudan; Surinam; Syria; Tanzania; Trinidad; Tunia; Uganda; United-Arab-Emirates; Zambia; Zimbabwe)
Lanikor (Russia)
Lanoxin PG (Malaysia; New-Zealand)
Lenoxin (Germany)
Lifusin (Taiwan)
Mapluxin (Mexico)
Purgoxin (South-Africa)
Toloxin (Thailand)

HCFA JCODE(S): J1160 up to 0.5 mg IM, IV

COST OF THERAPY: $76.65 (Heart Failure; Lanoxin Tablet; 0.25 mg; 1/day; 365 days)

Contact UsBrochure RequestShipping & ReturnsPrivacy PolicySite MapCompany InformationView Shopping Cart
eGeneralMedical.com™ and the contents of this site are Trademark and Copyright protected – All rights reserved 2000-2010.
Ordering Help
Shipping & Returns Help
Partner With Us
Our Policies
Contact the Webmaster with any questions regarding the content of this website.

eGeneralMedical.com - Health Care Supplies, Medical Equipment, Alternative Health,Stethoscopes, Blood Pressure Monitors, Scales/Body Fat Monitors, Diabetic Supplies, Air Purifiers, White Noise Machines, Vitamins, Massage/Spa., Medical PDA Software