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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (D's) » Doxycycline



DESCRIPTION

The ATRIDOXTM product* is a subgingival controlled-release product composed of a two syringe mixing system. Syringe A contains 450 mg of the ATRIGEL Delivery System, which is a bioabsorbable, flowable polymeric formulation composed of 36.7% poly( DL-lactide) (PLA) dissolved in 63.3% N-methyl-2-pyrrolidone (NMP). Syringe B contains doxycycline hyclate which is equivalent to 42.5 mg doxycycline. The constituted product is a pale yellow to yellow viscous liquid with a concentration of 8.5% w/w of doxycycline. Upon contact with the crevicular fluid, the liquid product solidifies and then allows for controlled release of drug for a period of 7 days.

*ATRIDOX is a trademark of Block Drug Corporation. ATRIGEL is a registered trademark of Atrix Laboratories, Inc.

Doxycycline is a broad-spectrum antibiotic synthetically derived from oxytetracycyline.

Empirical Formula: (C22H24N2O8 HCl)2 C2H8O H2O





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